Insulin resistance functionally limits endothelium-dependent coronary vasodilation in nondiabetic patients

Insulin resistance (IR) is now considered to be a risk factor for coronary arterial atherosclerosis and is likely to be involved in a limited endothelium-dependent vasodilatory function in peripheral circulation. We investigated whether IR impairs endothelial vasodilator function in the noninfarcted...

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Veröffentlicht in:	Heart and vessels 2008, Vol.23 (1), p.9-15
Hauptverfasser:	Fujii, Noriyuki, Tsuchihashi, Kazufumi, Sasao, Hisataka, Eguchi, Mariko, Miurakami, Hideyuki, Hase, Mamoru, Higashiura, Katsuhiro, Yuda, Satoshi, Hashimoto, Akiyoshi, Miura, Tetsuji, Ura, Nobuyuki, Shimamoto, Kazuaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biomedical Engineering and Bioengineering Blood Flow Velocity Blood Glucose - metabolism Cardiac Surgery Cardiology Cardiovascular disease Coronary Angiography Coronary Circulation - physiology Coronary Stenosis - blood Coronary Stenosis - diagnosis Coronary Stenosis - physiopathology Coronary vessels Coronary Vessels - diagnostic imaging Coronary Vessels - physiopathology Diabetes Mellitus Endothelium, Vascular - physiopathology Female Follow-Up Studies Glucose Clamp Technique Humans Insulin resistance Insulin Resistance - physiology Male Medicine Medicine & Public Health Metabolic disorders Middle Aged Original Article Prognosis Prospective Studies Risk Factors Ultrasonography, Doppler Vascular Surgery Vasodilation - physiology
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