Exonic, but not intronic polymorphisms of ESR1 gene might influence the hypolipemic effect of raloxifene

Studies have shown that selective modulator of estrogen receptor raloxifene, exerts hypolipemic properties at least partially through estrogen receptor alpha activation. To test the hypothesis that polymorphisms of estrogen receptor alpha are associated with the influence of 6 months raloxifene trea...

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Veröffentlicht in:	The Journal of steroid biochemistry and molecular biology 2007-04, Vol.104 (1), p.22-26
Hauptverfasser:	Zavratnik, Andrej, Preželj, Janez, Kocijančič, Andreja, Marc, Janja
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Cell receptors Cell structures and functions Cholesterol - blood Cholesterol, HDL - blood Cholesterol, LDL - blood Estrogen receptor alpha Estrogen Receptor alpha - genetics Exons - genetics Female Fundamental and applied biological sciences. Psychology Genotype Hormone receptors. Growth factor receptors. Cytokine receptors. Prostaglandin receptors Humans Introns - genetics Lipids Lipids - blood Middle Aged Molecular and cellular biology Polymorphism, Genetic Postmenopausal women Postmenopause Raloxifene Raloxifene Hydrochloride - therapeutic use Selective Estrogen Receptor Modulators - therapeutic use Triglycerides - blood
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