Magnetic Force Microscopy of Superparamagnetic Nanoparticles
The use of magnetic force microscopy (MFM) to detect probe–sample interactions from superparamagnetic nanoparticles in vitro in ambient atmospheric conditions is reported here. By using both magnetic and nonmagnetic probes in dynamic lift‐mode imaging and by controlling the direction and magnitude o...
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| Veröffentlicht in: | Small (Weinheim an der Bergstrasse, Germany) Germany), 2008-02, Vol.4 (2), p.270-278 |
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| container_title | Small (Weinheim an der Bergstrasse, Germany) |
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| creator | Schreiber, Sharon Savla, Mayur Pelekhov, Denis V. Iscru, Daniel F. Selcu, Camelia Hammel, P. Chris Agarwal, Gunjan |
| description | The use of magnetic force microscopy (MFM) to detect probe–sample interactions from superparamagnetic nanoparticles in vitro in ambient atmospheric conditions is reported here. By using both magnetic and nonmagnetic probes in dynamic lift‐mode imaging and by controlling the direction and magnitude of the external magnetic field applied to the samples, it is possible to detect and identify the presence of superparamagnetic nanoparticles. The experimental results shown here are in agreement with the estimated sensitivity of the MFM technique. The potential and challenges for localizing nanoscale magnetic domains in biological samples is discussed.
Detecting nanomagnets: By using external magnetic fields and magnetic atomic force microscopy (MFM) tips, it is possible to identify the dipolar nature of superparamagnetic nanoparticles in ambient air (see figure). These approaches could help localize magnetic deposits in diseased tissues. |
| doi_str_mv | 10.1002/smll.200700116 |
| format | Article |
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Detecting nanomagnets: By using external magnetic fields and magnetic atomic force microscopy (MFM) tips, it is possible to identify the dipolar nature of superparamagnetic nanoparticles in ambient air (see figure). These approaches could help localize magnetic deposits in diseased tissues.</description><identifier>ISSN: 1613-6810</identifier><identifier>EISSN: 1613-6829</identifier><identifier>DOI: 10.1002/smll.200700116</identifier><identifier>PMID: 18247385</identifier><language>eng</language><publisher>Weinheim: WILEY-VCH Verlag</publisher><subject>Dipoles ; Ferrosoferric Oxide - chemistry ; Magnetic force microscopy ; Magnetic properties ; Magnetics ; Metal Nanoparticles - chemistry ; Metal Nanoparticles - ultrastructure ; Microscopy, Atomic Force - methods ; Microscopy, Atomic Force - statistics & numerical data ; Nanoparticles ; Particle Size ; Superparamagnetism</subject><ispartof>Small (Weinheim an der Bergstrasse, Germany), 2008-02, Vol.4 (2), p.270-278</ispartof><rights>Copyright © 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4786-77b01e775712c84af8a0d33547f00d2e13b74a62cb5d006d144d38820e064f003</citedby><cites>FETCH-LOGICAL-c4786-77b01e775712c84af8a0d33547f00d2e13b74a62cb5d006d144d38820e064f003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fsmll.200700116$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fsmll.200700116$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18247385$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schreiber, Sharon</creatorcontrib><creatorcontrib>Savla, Mayur</creatorcontrib><creatorcontrib>Pelekhov, Denis V.</creatorcontrib><creatorcontrib>Iscru, Daniel F.</creatorcontrib><creatorcontrib>Selcu, Camelia</creatorcontrib><creatorcontrib>Hammel, P. Chris</creatorcontrib><creatorcontrib>Agarwal, Gunjan</creatorcontrib><title>Magnetic Force Microscopy of Superparamagnetic Nanoparticles</title><title>Small (Weinheim an der Bergstrasse, Germany)</title><addtitle>Small</addtitle><description>The use of magnetic force microscopy (MFM) to detect probe–sample interactions from superparamagnetic nanoparticles in vitro in ambient atmospheric conditions is reported here. By using both magnetic and nonmagnetic probes in dynamic lift‐mode imaging and by controlling the direction and magnitude of the external magnetic field applied to the samples, it is possible to detect and identify the presence of superparamagnetic nanoparticles. The experimental results shown here are in agreement with the estimated sensitivity of the MFM technique. The potential and challenges for localizing nanoscale magnetic domains in biological samples is discussed.
Detecting nanomagnets: By using external magnetic fields and magnetic atomic force microscopy (MFM) tips, it is possible to identify the dipolar nature of superparamagnetic nanoparticles in ambient air (see figure). These approaches could help localize magnetic deposits in diseased tissues.</description><subject>Dipoles</subject><subject>Ferrosoferric Oxide - chemistry</subject><subject>Magnetic force microscopy</subject><subject>Magnetic properties</subject><subject>Magnetics</subject><subject>Metal Nanoparticles - chemistry</subject><subject>Metal Nanoparticles - ultrastructure</subject><subject>Microscopy, Atomic Force - methods</subject><subject>Microscopy, Atomic Force - statistics & numerical data</subject><subject>Nanoparticles</subject><subject>Particle Size</subject><subject>Superparamagnetism</subject><issn>1613-6810</issn><issn>1613-6829</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMFPwjAUhxujEUSvHs1O3oav7daWxIshgkbARDAcm67rzHRjs2VR_ntLhuiN03t5-X5f8n4IXWLoYwBy48qi6BMADoAxO0JdzDANmSCD4_2OoYPOnHsHoJhE_BR1sPCTiriLbqfqbWXWuQ5GldUmmObaVk5X9SaosmDe1MbWyqryl5qpVeUPfi2MO0cnmSqcudjNHnod3S-GD-Hkefw4vJuEOuKChZwngA3nMcdEi0hlQkFKaRzxDCAlBtOER4oRncQpAEtxFKVUCAIGWOQR2kPXrbe21Wdj3FqWudOmKNTKVI2THIgQMRYHQUqA8RioB_stuP3WWZPJ2ualshuJQW6Lldti5b5YH7jamZukNOkfvmvSA4MW-MoLszmgk_PpZPJfHrbZ3K3N9z6r7IdknPJYLmdjOX5akuXLwvvoD76Akp8</recordid><startdate>20080201</startdate><enddate>20080201</enddate><creator>Schreiber, Sharon</creator><creator>Savla, Mayur</creator><creator>Pelekhov, Denis V.</creator><creator>Iscru, Daniel F.</creator><creator>Selcu, Camelia</creator><creator>Hammel, P. 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Chris</au><au>Agarwal, Gunjan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Magnetic Force Microscopy of Superparamagnetic Nanoparticles</atitle><jtitle>Small (Weinheim an der Bergstrasse, Germany)</jtitle><addtitle>Small</addtitle><date>2008-02-01</date><risdate>2008</risdate><volume>4</volume><issue>2</issue><spage>270</spage><epage>278</epage><pages>270-278</pages><issn>1613-6810</issn><eissn>1613-6829</eissn><abstract>The use of magnetic force microscopy (MFM) to detect probe–sample interactions from superparamagnetic nanoparticles in vitro in ambient atmospheric conditions is reported here. By using both magnetic and nonmagnetic probes in dynamic lift‐mode imaging and by controlling the direction and magnitude of the external magnetic field applied to the samples, it is possible to detect and identify the presence of superparamagnetic nanoparticles. The experimental results shown here are in agreement with the estimated sensitivity of the MFM technique. The potential and challenges for localizing nanoscale magnetic domains in biological samples is discussed.
Detecting nanomagnets: By using external magnetic fields and magnetic atomic force microscopy (MFM) tips, it is possible to identify the dipolar nature of superparamagnetic nanoparticles in ambient air (see figure). These approaches could help localize magnetic deposits in diseased tissues.</abstract><cop>Weinheim</cop><pub>WILEY-VCH Verlag</pub><pmid>18247385</pmid><doi>10.1002/smll.200700116</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Dipoles Ferrosoferric Oxide - chemistry Magnetic force microscopy Magnetic properties Magnetics Metal Nanoparticles - chemistry Metal Nanoparticles - ultrastructure Microscopy, Atomic Force - methods Microscopy, Atomic Force - statistics & numerical data Nanoparticles Particle Size Superparamagnetism |
| title | Magnetic Force Microscopy of Superparamagnetic Nanoparticles |
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