Adenosine Modulates Cardiovascular Functions Through Activation of Extracellular Signal-Regulated Kinases 1 and 2 and Endothelial Nitric Oxide Synthase in the Nucleus Tractus Solitarii of Rats

The nucleus tractus solitarius (NTS) is the primary integrative center for baroreflex. Adenosine has been shown to play an important modulatory role in blood pressure control in the NTS. Our previous results demonstrated that adenosine decreases blood pressure, heart rate, and renal sympathetic nerv...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2008-02, Vol.117 (6), p.773-780
Hauptverfasser:	HO, Wen-Yu, LU, Pei-Jung, HSIAO, Michael, HWANG, Hwong-Ru, TSENG, Yu-Chou, YEN, Mao-Hsiung, TSENG, Ching-Jiunn
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - pharmacology Adenosine - physiology Animals Biological and medical sciences Blood and lymphatic vessels Blood Pressure - drug effects Cardiology. Vascular system Cardiovascular Physiological Phenomena Coronary heart disease Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Heart Heart Rate - drug effects Male Medical sciences Mitogen-Activated Protein Kinase 1 - metabolism Mitogen-Activated Protein Kinase 3 - metabolism Nitric Oxide Synthase Type III - metabolism Rats Rats, Sprague-Dawley Signal Transduction - drug effects Signal Transduction - physiology Solitary Nucleus - metabolism
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