An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members

GAGE cancer/testis antigens are frequently expressed in many different types of cancer, whereas their expression in normal tissues is limited to the germ cells of the immune‐privileged organs, testis and ovary. Thus, GAGE proteins may be attractive candidates for immunotherapy of cancer. This review...

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Veröffentlicht in:	Tissue antigens 2008-03, Vol.71 (3), p.187-192
Hauptverfasser:	Gjerstorff, M. F., Ditzel, H. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Neoplasm - classification Antigens, Neoplasm - genetics Base Sequence cancer immunotherapy cancer/testis antigen Chromosomes, Human, X - genetics DNA - genetics DNA, Neoplasm - genetics Female GAGE Gene Expression human chromosome X Humans Immunotherapy Male Molecular Sequence Data Multigene Family Neoplasm Proteins - classification Neoplasm Proteins - genetics Neoplasm Proteins - immunology Neoplasms - genetics Neoplasms - immunology Neoplasms - therapy Phylogeny RNA, Messenger - genetics RNA, Neoplasm - genetics Sequence Homology, Nucleic Acid tandem repeats Testis - immunology unequal replication
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