Coronary Artery Calcifications in Hemodialysis Patients and Their Correlation With the Prevalence of Erectile Dysfunction

Abstract Introduction Our aim in this study was to investigate the prevalence and correlation with coronary artery calcium scores (CACS) and erectile dysfunction (ED) among hemodialysis patients. Patients and methods Thirty-five male patients with chronic renal failure were selected to participate i...

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Veröffentlicht in:Transplantation proceedings 2008, Vol.40 (1), p.77-80
Hauptverfasser: Inci, K, Hazırolan, T, Aki, F.T, Oruc, O, Tombul, T, Tasar, C, Erkan, I, Bakkaloglu, M, Turgan, C, Ergen, A
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container_end_page 80
container_issue 1
container_start_page 77
container_title Transplantation proceedings
container_volume 40
creator Inci, K
Hazırolan, T
Aki, F.T
Oruc, O
Tombul, T
Tasar, C
Erkan, I
Bakkaloglu, M
Turgan, C
Ergen, A
description Abstract Introduction Our aim in this study was to investigate the prevalence and correlation with coronary artery calcium scores (CACS) and erectile dysfunction (ED) among hemodialysis patients. Patients and methods Thirty-five male patients with chronic renal failure were selected to participate in this study. All patients underwent examinations for CACS using 16-channel multidetector computed tomography. The presence and severity of ED were determined by calculating the erectile function domain of the self-administered International Index of Erectile Function (IIEF). Results The patients’ ages ranged from 22 to 78 with a mean of 51.6 years. The mean duration of hemodialysis was 75.7 months (range = 12 to 232). Twenty-six patients had a history of one or more systemic diseases. The prevalence of any level of ED was 82.9% for all hemodialysis patients, and severe ED, 40%. The CACS was significantly higher among patients with severe ED ( P = .032). The IIEF-5 score was also shown to have a moderate negative correlation with the CACS ( r = −.420, P = .012). Age, duration of hemodialysis, body mass index, diabetes mellitus, hypertension, coronary heart diseases, hyperlipidemia, thyroid disease, depression, tobacco consumption, and medication were not associated with the presence of ED ( P > .05). Conclusion ED is prevalent in hemodialysis patients. Although many possible factors contribute to ED, the severity of ED increases with greater CACS.
doi_str_mv 10.1016/j.transproceed.2007.11.046
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Patients and methods Thirty-five male patients with chronic renal failure were selected to participate in this study. All patients underwent examinations for CACS using 16-channel multidetector computed tomography. The presence and severity of ED were determined by calculating the erectile function domain of the self-administered International Index of Erectile Function (IIEF). Results The patients’ ages ranged from 22 to 78 with a mean of 51.6 years. The mean duration of hemodialysis was 75.7 months (range = 12 to 232). Twenty-six patients had a history of one or more systemic diseases. The prevalence of any level of ED was 82.9% for all hemodialysis patients, and severe ED, 40%. The CACS was significantly higher among patients with severe ED ( P = .032). The IIEF-5 score was also shown to have a moderate negative correlation with the CACS ( r = −.420, P = .012). Age, duration of hemodialysis, body mass index, diabetes mellitus, hypertension, coronary heart diseases, hyperlipidemia, thyroid disease, depression, tobacco consumption, and medication were not associated with the presence of ED ( P &gt; .05). Conclusion ED is prevalent in hemodialysis patients. Although many possible factors contribute to ED, the severity of ED increases with greater CACS.</description><identifier>ISSN: 0041-1345</identifier><identifier>EISSN: 1873-2623</identifier><identifier>DOI: 10.1016/j.transproceed.2007.11.046</identifier><identifier>PMID: 18261550</identifier><identifier>CODEN: TRPPA8</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Aged ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Calcinosis - complications ; Calcinosis - diagnostic imaging ; Calcinosis - epidemiology ; Coronary Disease - complications ; Coronary Disease - diagnostic imaging ; Coronary Disease - epidemiology ; Emergency and intensive care: renal failure. Dialysis management ; Erectile Dysfunction - complications ; Erectile Dysfunction - diagnostic imaging ; Erectile Dysfunction - epidemiology ; Fundamental and applied biological sciences. Psychology ; Fundamental immunology ; Humans ; Intensive care medicine ; Kidney Failure, Chronic - complications ; Kidney Failure, Chronic - therapy ; Male ; Medical sciences ; Middle Aged ; Prevalence ; Renal Dialysis - adverse effects ; Surgery ; Surgery (general aspects). Transplantations, organ and tissue grafts. 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Patients and methods Thirty-five male patients with chronic renal failure were selected to participate in this study. All patients underwent examinations for CACS using 16-channel multidetector computed tomography. The presence and severity of ED were determined by calculating the erectile function domain of the self-administered International Index of Erectile Function (IIEF). Results The patients’ ages ranged from 22 to 78 with a mean of 51.6 years. The mean duration of hemodialysis was 75.7 months (range = 12 to 232). Twenty-six patients had a history of one or more systemic diseases. The prevalence of any level of ED was 82.9% for all hemodialysis patients, and severe ED, 40%. The CACS was significantly higher among patients with severe ED ( P = .032). The IIEF-5 score was also shown to have a moderate negative correlation with the CACS ( r = −.420, P = .012). Age, duration of hemodialysis, body mass index, diabetes mellitus, hypertension, coronary heart diseases, hyperlipidemia, thyroid disease, depression, tobacco consumption, and medication were not associated with the presence of ED ( P &gt; .05). Conclusion ED is prevalent in hemodialysis patients. Although many possible factors contribute to ED, the severity of ED increases with greater CACS.</description><subject>Adult</subject><subject>Aged</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Calcinosis - complications</subject><subject>Calcinosis - diagnostic imaging</subject><subject>Calcinosis - epidemiology</subject><subject>Coronary Disease - complications</subject><subject>Coronary Disease - diagnostic imaging</subject><subject>Coronary Disease - epidemiology</subject><subject>Emergency and intensive care: renal failure. 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Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Calcinosis - complications</topic><topic>Calcinosis - diagnostic imaging</topic><topic>Calcinosis - epidemiology</topic><topic>Coronary Disease - complications</topic><topic>Coronary Disease - diagnostic imaging</topic><topic>Coronary Disease - epidemiology</topic><topic>Emergency and intensive care: renal failure. Dialysis management</topic><topic>Erectile Dysfunction - complications</topic><topic>Erectile Dysfunction - diagnostic imaging</topic><topic>Erectile Dysfunction - epidemiology</topic><topic>Fundamental and applied biological sciences. 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Patients and methods Thirty-five male patients with chronic renal failure were selected to participate in this study. All patients underwent examinations for CACS using 16-channel multidetector computed tomography. The presence and severity of ED were determined by calculating the erectile function domain of the self-administered International Index of Erectile Function (IIEF). Results The patients’ ages ranged from 22 to 78 with a mean of 51.6 years. The mean duration of hemodialysis was 75.7 months (range = 12 to 232). Twenty-six patients had a history of one or more systemic diseases. The prevalence of any level of ED was 82.9% for all hemodialysis patients, and severe ED, 40%. The CACS was significantly higher among patients with severe ED ( P = .032). The IIEF-5 score was also shown to have a moderate negative correlation with the CACS ( r = −.420, P = .012). Age, duration of hemodialysis, body mass index, diabetes mellitus, hypertension, coronary heart diseases, hyperlipidemia, thyroid disease, depression, tobacco consumption, and medication were not associated with the presence of ED ( P &gt; .05). Conclusion ED is prevalent in hemodialysis patients. Although many possible factors contribute to ED, the severity of ED increases with greater CACS.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>18261550</pmid><doi>10.1016/j.transproceed.2007.11.046</doi><tpages>4</tpages></addata></record>
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subjects Adult
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Calcinosis - complications
Calcinosis - diagnostic imaging
Calcinosis - epidemiology
Coronary Disease - complications
Coronary Disease - diagnostic imaging
Coronary Disease - epidemiology
Emergency and intensive care: renal failure. Dialysis management
Erectile Dysfunction - complications
Erectile Dysfunction - diagnostic imaging
Erectile Dysfunction - epidemiology
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Humans
Intensive care medicine
Kidney Failure, Chronic - complications
Kidney Failure, Chronic - therapy
Male
Medical sciences
Middle Aged
Prevalence
Renal Dialysis - adverse effects
Surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Time Factors
Tissue, organ and graft immunology
Tomography, X-Ray Computed
title Coronary Artery Calcifications in Hemodialysis Patients and Their Correlation With the Prevalence of Erectile Dysfunction
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