A systematic look at an old problem
As life expectancy increases, a systems-biology approach is needed to ensure that we have a healthy old age. Research Horizons A new series begins this week. 'Horizons' are commissioned articles in which experts speculate on what will happen over the next few years in their fields. On the...
Gespeichert in:
| Veröffentlicht in: | Nature (London) 2008-02, Vol.451 (7179), p.644-647 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 647 |
|---|---|
| container_issue | 7179 |
| container_start_page | 644 |
| container_title | Nature (London) |
| container_volume | 451 |
| creator | Kirkwood, Thomas B. L. |
| description | As life expectancy increases, a systems-biology approach is needed to ensure that we have a healthy old age.
Research Horizons
A new series begins this week. 'Horizons' are commissioned articles in which experts speculate on what will happen over the next few years in their fields. On the cover, one of Antony Gormley's figures in his
Another Place
installation sets the tone. In the first piece, Thomas Kirkwood considers the potential of systems biology to de-link disease and old age. Peter Murray-Rust writes on a new 'open' approach to chemistry. But his subtext is broader: the future of the 'semantic web', where computers can make as much use of information as humans can. M. Armand and J.-M. Tarascon show how advances in materials science can provide the batteries of the future. George Koentges tackles 'evo-devo', the marriage of fossil evidence, genomic sequencing and molecular developmental biology. And R. J. Schoelkopf and S. M. Girvin raise the prospect that circuit quantum electrodynamics could pave the way for practical quantum computing and communication. On page
643
,
Nature
editor Philip Campbell sets out the brief for these and future Horizons. |
| doi_str_mv | 10.1038/451644a |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_70276300</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A193476476</galeid><sourcerecordid>A193476476</sourcerecordid><originalsourceid>FETCH-LOGICAL-c543t-24fde847fdedc24b8a8e6ec7ab580d750deef6dfeeedf74f4323326f81c396193</originalsourceid><addsrcrecordid>eNp10ltrFDEUAOAgil2r-A9ksHhDpuae9HFZvBSKglZ8DNnkZJmamWyTGbD_3sgOrlsqCQkkX84Jh4PQU4JPCWb6HRdEcm7voQXhSrZcanUfLTCmusWaySP0qJQrjLEgij9ER0RTIaXQC3SybMpNGaG3Y-eamNLPxo6NHZoUfbPNaR2hf4weBBsLPJn3Y_T9w_vL1af24svH89XyonWCs7GlPHjQXNXVO8rX2mqQ4JRdC429EtgDBOkDAPigeOCMMkZl0MSxM0nO2DF6uYtb815PUEbTd8VBjHaANBWjMFWSYVzh81vwKk15qH8zFHMhOGG6onaHNjaC6YaQxmzdBgbINqYBQlePlzVtLVid-6AH3m27a_MvOr0D1eGh79ydUd8cPKhmhF_jxk6lmPNvXw_t2__b5eWP1edD_WqnXU6lZAhmm7ve5htDsPnTFGZuiiqfzeWa1j34vZu7oIIXM7DF2RiyHVxX_jpaS66Y5NW93rlSr4YN5H3db-f8DTqdxQU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>204554138</pqid></control><display><type>article</type><title>A systematic look at an old problem</title><source>MEDLINE</source><source>Springer Nature - Connect here FIRST to enable access</source><source>SpringerLink Journals - AutoHoldings</source><creator>Kirkwood, Thomas B. L.</creator><creatorcontrib>Kirkwood, Thomas B. L.</creatorcontrib><description>As life expectancy increases, a systems-biology approach is needed to ensure that we have a healthy old age.
Research Horizons
A new series begins this week. 'Horizons' are commissioned articles in which experts speculate on what will happen over the next few years in their fields. On the cover, one of Antony Gormley's figures in his
Another Place
installation sets the tone. In the first piece, Thomas Kirkwood considers the potential of systems biology to de-link disease and old age. Peter Murray-Rust writes on a new 'open' approach to chemistry. But his subtext is broader: the future of the 'semantic web', where computers can make as much use of information as humans can. M. Armand and J.-M. Tarascon show how advances in materials science can provide the batteries of the future. George Koentges tackles 'evo-devo', the marriage of fossil evidence, genomic sequencing and molecular developmental biology. And R. J. Schoelkopf and S. M. Girvin raise the prospect that circuit quantum electrodynamics could pave the way for practical quantum computing and communication. On page
643
,
Nature
editor Philip Campbell sets out the brief for these and future Horizons.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/451644a</identifier><identifier>PMID: 18256658</identifier><identifier>CODEN: NATUAS</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Age Distribution ; Aging ; Aging - physiology ; Animals ; Biological and medical sciences ; Biological research ; Biology, Experimental ; Caenorhabditis elegans - genetics ; Caenorhabditis elegans - physiology ; Disease Models, Animal ; DNA Damage ; Evaluation ; General aspects ; Geriatrics - trends ; Health ; horizons ; Humanities and Social Sciences ; Humans ; Life expectancy ; Life Expectancy - trends ; Longevity - physiology ; Medical research ; Medical sciences ; Mice ; Models, Biological ; multidisciplinary ; Neoplasms - epidemiology ; Neoplasms - pathology ; Planification. Prevention (methods). Intervention. Evaluation ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Science ; Science (multidisciplinary) ; Scientific discoveries ; Systems Biology ; Werner Syndrome - genetics ; Werner Syndrome - pathology</subject><ispartof>Nature (London), 2008-02, Vol.451 (7179), p.644-647</ispartof><rights>Springer Nature Limited 2008</rights><rights>2008 INIST-CNRS</rights><rights>COPYRIGHT 2008 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Feb 7, 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c543t-24fde847fdedc24b8a8e6ec7ab580d750deef6dfeeedf74f4323326f81c396193</citedby><cites>FETCH-LOGICAL-c543t-24fde847fdedc24b8a8e6ec7ab580d750deef6dfeeedf74f4323326f81c396193</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1038/451644a$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1038/451644a$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20037364$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18256658$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kirkwood, Thomas B. L.</creatorcontrib><title>A systematic look at an old problem</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>As life expectancy increases, a systems-biology approach is needed to ensure that we have a healthy old age.
Research Horizons
A new series begins this week. 'Horizons' are commissioned articles in which experts speculate on what will happen over the next few years in their fields. On the cover, one of Antony Gormley's figures in his
Another Place
installation sets the tone. In the first piece, Thomas Kirkwood considers the potential of systems biology to de-link disease and old age. Peter Murray-Rust writes on a new 'open' approach to chemistry. But his subtext is broader: the future of the 'semantic web', where computers can make as much use of information as humans can. M. Armand and J.-M. Tarascon show how advances in materials science can provide the batteries of the future. George Koentges tackles 'evo-devo', the marriage of fossil evidence, genomic sequencing and molecular developmental biology. And R. J. Schoelkopf and S. M. Girvin raise the prospect that circuit quantum electrodynamics could pave the way for practical quantum computing and communication. On page
643
,
Nature
editor Philip Campbell sets out the brief for these and future Horizons.</description><subject>Age Distribution</subject><subject>Aging</subject><subject>Aging - physiology</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Biological research</subject><subject>Biology, Experimental</subject><subject>Caenorhabditis elegans - genetics</subject><subject>Caenorhabditis elegans - physiology</subject><subject>Disease Models, Animal</subject><subject>DNA Damage</subject><subject>Evaluation</subject><subject>General aspects</subject><subject>Geriatrics - trends</subject><subject>Health</subject><subject>horizons</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Life expectancy</subject><subject>Life Expectancy - trends</subject><subject>Longevity - physiology</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Models, Biological</subject><subject>multidisciplinary</subject><subject>Neoplasms - epidemiology</subject><subject>Neoplasms - pathology</subject><subject>Planification. Prevention (methods). Intervention. Evaluation</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Scientific discoveries</subject><subject>Systems Biology</subject><subject>Werner Syndrome - genetics</subject><subject>Werner Syndrome - pathology</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp10ltrFDEUAOAgil2r-A9ksHhDpuae9HFZvBSKglZ8DNnkZJmamWyTGbD_3sgOrlsqCQkkX84Jh4PQU4JPCWb6HRdEcm7voQXhSrZcanUfLTCmusWaySP0qJQrjLEgij9ER0RTIaXQC3SybMpNGaG3Y-eamNLPxo6NHZoUfbPNaR2hf4weBBsLPJn3Y_T9w_vL1af24svH89XyonWCs7GlPHjQXNXVO8rX2mqQ4JRdC429EtgDBOkDAPigeOCMMkZl0MSxM0nO2DF6uYtb815PUEbTd8VBjHaANBWjMFWSYVzh81vwKk15qH8zFHMhOGG6onaHNjaC6YaQxmzdBgbINqYBQlePlzVtLVid-6AH3m27a_MvOr0D1eGh79ydUd8cPKhmhF_jxk6lmPNvXw_t2__b5eWP1edD_WqnXU6lZAhmm7ve5htDsPnTFGZuiiqfzeWa1j34vZu7oIIXM7DF2RiyHVxX_jpaS66Y5NW93rlSr4YN5H3db-f8DTqdxQU</recordid><startdate>20080207</startdate><enddate>20080207</enddate><creator>Kirkwood, Thomas B. L.</creator><general>Nature Publishing Group UK</general><general>Nature Publishing</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ATWCN</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QP</scope><scope>7QR</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7ST</scope><scope>7T5</scope><scope>7TG</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PCBAR</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>R05</scope><scope>RC3</scope><scope>S0X</scope><scope>SOI</scope><scope>7X8</scope></search><sort><creationdate>20080207</creationdate><title>A systematic look at an old problem</title><author>Kirkwood, Thomas B. L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c543t-24fde847fdedc24b8a8e6ec7ab580d750deef6dfeeedf74f4323326f81c396193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Age Distribution</topic><topic>Aging</topic><topic>Aging - physiology</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Biological research</topic><topic>Biology, Experimental</topic><topic>Caenorhabditis elegans - genetics</topic><topic>Caenorhabditis elegans - physiology</topic><topic>Disease Models, Animal</topic><topic>DNA Damage</topic><topic>Evaluation</topic><topic>General aspects</topic><topic>Geriatrics - trends</topic><topic>Health</topic><topic>horizons</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>Life expectancy</topic><topic>Life Expectancy - trends</topic><topic>Longevity - physiology</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Models, Biological</topic><topic>multidisciplinary</topic><topic>Neoplasms - epidemiology</topic><topic>Neoplasms - pathology</topic><topic>Planification. Prevention (methods). Intervention. Evaluation</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Scientific discoveries</topic><topic>Systems Biology</topic><topic>Werner Syndrome - genetics</topic><topic>Werner Syndrome - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kirkwood, Thomas B. L.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Middle School</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Environment Abstracts</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database (Proquest)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Database (1962 - current)</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Earth, Atmospheric & Aquatic Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>Biological Sciences</collection><collection>Agriculture Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Psychology Database (ProQuest)</collection><collection>ProQuest Research Library</collection><collection>Science Database (ProQuest)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest advanced technologies & aerospace journals</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Earth, Atmospheric & Aquatic Science Database</collection><collection>Materials Science Collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>Engineering collection</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>University of Michigan</collection><collection>Genetics Abstracts</collection><collection>SIRS Editorial</collection><collection>Environment Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kirkwood, Thomas B. L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A systematic look at an old problem</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>2008-02-07</date><risdate>2008</risdate><volume>451</volume><issue>7179</issue><spage>644</spage><epage>647</epage><pages>644-647</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><coden>NATUAS</coden><abstract>As life expectancy increases, a systems-biology approach is needed to ensure that we have a healthy old age.
Research Horizons
A new series begins this week. 'Horizons' are commissioned articles in which experts speculate on what will happen over the next few years in their fields. On the cover, one of Antony Gormley's figures in his
Another Place
installation sets the tone. In the first piece, Thomas Kirkwood considers the potential of systems biology to de-link disease and old age. Peter Murray-Rust writes on a new 'open' approach to chemistry. But his subtext is broader: the future of the 'semantic web', where computers can make as much use of information as humans can. M. Armand and J.-M. Tarascon show how advances in materials science can provide the batteries of the future. George Koentges tackles 'evo-devo', the marriage of fossil evidence, genomic sequencing and molecular developmental biology. And R. J. Schoelkopf and S. M. Girvin raise the prospect that circuit quantum electrodynamics could pave the way for practical quantum computing and communication. On page
643
,
Nature
editor Philip Campbell sets out the brief for these and future Horizons.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>18256658</pmid><doi>10.1038/451644a</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-0836 |
| ispartof | Nature (London), 2008-02, Vol.451 (7179), p.644-647 |
| issn | 0028-0836 1476-4687 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70276300 |
| source | MEDLINE; Springer Nature - Connect here FIRST to enable access; SpringerLink Journals - AutoHoldings |
| subjects | Age Distribution Aging Aging - physiology Animals Biological and medical sciences Biological research Biology, Experimental Caenorhabditis elegans - genetics Caenorhabditis elegans - physiology Disease Models, Animal DNA Damage Evaluation General aspects Geriatrics - trends Health horizons Humanities and Social Sciences Humans Life expectancy Life Expectancy - trends Longevity - physiology Medical research Medical sciences Mice Models, Biological multidisciplinary Neoplasms - epidemiology Neoplasms - pathology Planification. Prevention (methods). Intervention. Evaluation Public health. Hygiene Public health. Hygiene-occupational medicine Science Science (multidisciplinary) Scientific discoveries Systems Biology Werner Syndrome - genetics Werner Syndrome - pathology |
| title | A systematic look at an old problem |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T01%3A55%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20systematic%20look%20at%20an%20old%20problem&rft.jtitle=Nature%20(London)&rft.au=Kirkwood,%20Thomas%20B.%20L.&rft.date=2008-02-07&rft.volume=451&rft.issue=7179&rft.spage=644&rft.epage=647&rft.pages=644-647&rft.issn=0028-0836&rft.eissn=1476-4687&rft.coden=NATUAS&rft_id=info:doi/10.1038/451644a&rft_dat=%3Cgale_proqu%3EA193476476%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=204554138&rft_id=info:pmid/18256658&rft_galeid=A193476476&rfr_iscdi=true |