Latex of immunodiagnosis for detecting the Chagas disease: II. Chemical coupling of antigen Ag36 onto carboxylated latexes

A novel immunodiagnosis reagent for detecting the Chagas Disease was developed, by chemical coupling of antigen Ag36 of Trypanosoma cruzi onto two (carboxylated and core-shell) latexes. The coupling reactions involved the use of a carbodiimide intermediate. Bovine serum albumin (BSA) was used as a m...

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Veröffentlicht in:	Journal of materials science. Materials in medicine 2008-02, Vol.19 (2), p.789-795
Hauptverfasser:	Gonzalez, Verónica D. G., Gugliotta, Luis M., Giacomelli, Carla E., Meira, Gregorio R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Protozoan - chemistry Antibodies, Protozoan - immunology Antigens Antigens, Protozoan - chemistry Biomaterials Biomedical Engineering and Bioengineering Biomedical materials Carboxylated Ceramics Chagas Disease - diagnosis Chemistry and Materials Science Composites Covalence Density Disease Glass Humans Immunoassay - instrumentation Immunologic Tests Joining Latex Latex - chemical synthesis Materials Science Materials Testing Medical diagnosis Natural Materials Polymer Sciences Proteins Regenerative Medicine/Tissue Engineering Serum Albumin, Bovine - chemistry Studies Surfaces and Interfaces Thin Films Trypanosoma cruzi Trypanosoma cruzi - immunology
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