Rhodococcus equi lung infection in an allogeneic hematopoietic stem cell transplant recipient
: In this report, we describe a case of Rhodococcus equi lung infection diagnosed in an allogeneic hematopoietic stem cell transplant with oral graft‐versus‐host disease 3 months after stem cell infusion. The lung lesion persisted despite an approximate 3 months of vancomycin therapy, but then respo...
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| Veröffentlicht in: | Transplant infectious disease 2008-02, Vol.10 (1), p.48-51 |
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| container_title | Transplant infectious disease |
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| creator | Cronin, S.M. Abidi, M.H. Shearer, C.J. Chandrasekar, P.H. Ibrahim, R.B. |
| description | : In this report, we describe a case of Rhodococcus equi lung infection diagnosed in an allogeneic hematopoietic stem cell transplant with oral graft‐versus‐host disease 3 months after stem cell infusion. The lung lesion persisted despite an approximate 3 months of vancomycin therapy, but then responded favorably to a combination of intravenous ertapenem at 1 g daily and oral rifampin at 600 mg daily for 1 month. An overview of Rhodococcus infection in transplant recipients is presented. This case and the discussed literature suggest that combination antibiotic therapy is warranted in patients with decreased humoral and cellular immunity. |
| doi_str_mv | 10.1111/j.1399-3062.2007.00274.x |
| format | Article |
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The lung lesion persisted despite an approximate 3 months of vancomycin therapy, but then responded favorably to a combination of intravenous ertapenem at 1 g daily and oral rifampin at 600 mg daily for 1 month. An overview of Rhodococcus infection in transplant recipients is presented. 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The lung lesion persisted despite an approximate 3 months of vancomycin therapy, but then responded favorably to a combination of intravenous ertapenem at 1 g daily and oral rifampin at 600 mg daily for 1 month. An overview of Rhodococcus infection in transplant recipients is presented. This case and the discussed literature suggest that combination antibiotic therapy is warranted in patients with decreased humoral and cellular immunity.</description><subject>Actinomycetales Infections - diagnostic imaging</subject><subject>Actinomycetales Infections - microbiology</subject><subject>allogeneic</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>antibiotics</subject><subject>beta-Lactams - therapeutic use</subject><subject>combination</subject><subject>Drug Therapy, Combination</subject><subject>Graft vs Host Disease - complications</subject><subject>graft‐versus‐host‐disease</subject><subject>Hematopoietic Stem Cell Transplantation - adverse effects</subject><subject>Humans</subject><subject>Lung Diseases - diagnostic imaging</subject><subject>Lung Diseases - microbiology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Radiography</subject><subject>Rhodococcus</subject><subject>Rhodococcus equi - isolation & purification</subject><subject>Rifampin - therapeutic use</subject><subject>stem cell</subject><subject>transplant</subject><subject>Transplantation, Homologous - adverse effects</subject><issn>1398-2273</issn><issn>1399-3062</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1LxDAQhoMoun78BcnJW2vSpE0DXsTPBUGQ9SghzU41S9rUpsX135vuLno1DOQN885M5kEIU5LSeC5XKWVSJowUWZoRIlJCMsHT9R6a_Sb2N7pMskywI3QcwooQKiSXh-iICkE5Z-UMvb18-KU33pgxYPgcLXZj-45tW4MZrG-jwjqGc_4dWrAGf0CjB995C0N8hQEabMA5PPS6DZ3T7YB7MLaz0A6n6KDWLsDZ7j5Br_d3i5vH5On5YX5z_ZQYVhQ8kZLKOpe6rkrBc8oZk4QACMMyrWte6WkfamIqN5msmKEmL3S9FLTMC1pwdoIutn273n-OEAbV2DD9Srfgx6BExMNKWkRjuTWa3ofQQ6263ja6_1aUqAmtWqmJoJomqgmt2qBV61h6vpsxVg0s_wp3LKPhamv4sg6-_91YLea3UbAfbtaH7w</recordid><startdate>200802</startdate><enddate>200802</enddate><creator>Cronin, S.M.</creator><creator>Abidi, M.H.</creator><creator>Shearer, C.J.</creator><creator>Chandrasekar, P.H.</creator><creator>Ibrahim, R.B.</creator><general>Blackwell Publishing Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200802</creationdate><title>Rhodococcus equi lung infection in an allogeneic hematopoietic stem cell transplant recipient</title><author>Cronin, S.M. ; 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The lung lesion persisted despite an approximate 3 months of vancomycin therapy, but then responded favorably to a combination of intravenous ertapenem at 1 g daily and oral rifampin at 600 mg daily for 1 month. An overview of Rhodococcus infection in transplant recipients is presented. This case and the discussed literature suggest that combination antibiotic therapy is warranted in patients with decreased humoral and cellular immunity.</abstract><cop>Malden, USA</cop><pub>Blackwell Publishing Inc</pub><pmid>17714438</pmid><doi>10.1111/j.1399-3062.2007.00274.x</doi><tpages>4</tpages></addata></record> |
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| ispartof | Transplant infectious disease, 2008-02, Vol.10 (1), p.48-51 |
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| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Actinomycetales Infections - diagnostic imaging Actinomycetales Infections - microbiology allogeneic Anti-Bacterial Agents - therapeutic use antibiotics beta-Lactams - therapeutic use combination Drug Therapy, Combination Graft vs Host Disease - complications graft‐versus‐host‐disease Hematopoietic Stem Cell Transplantation - adverse effects Humans Lung Diseases - diagnostic imaging Lung Diseases - microbiology Male Middle Aged Radiography Rhodococcus Rhodococcus equi - isolation & purification Rifampin - therapeutic use stem cell transplant Transplantation, Homologous - adverse effects |
| title | Rhodococcus equi lung infection in an allogeneic hematopoietic stem cell transplant recipient |
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