Effect of estrogen replacement therapy on arthritis and bone mineral density in estrogen-replete rats with collagen-induced arthritis

Abstract The influence of estrogen therapy on changes in arthritis and bone mineral density (BMD) was evaluated using an estrogen-replete collagen-induced arthritis (CIA) rat model. Seven-month-old female Sprague-Dawley rats (n = 30) were divided into the three groups; control (CONT), collagen sensi...

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Veröffentlicht in:	Modern rheumatology 2008-02, Vol.18 (1), p.23-28
Hauptverfasser:	Yoshioka, Takeshi, Hagino, Hiroshi, Yamasaki, Daisuke, Okano, Toru, Teshima, Ryota
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis, Experimental - drug therapy Arthritis, Experimental - physiopathology Bone Density - drug effects Bone Density - physiology Collagen-induced arthritis Disease Models, Animal Estradiol - pharmacology Estrogen Estrogen Replacement Therapy Estrogens - pharmacology Female Histomorphometry Osteoporosis Osteoporosis - drug therapy Osteoporosis - physiopathology Rats
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