Doxorubicin eluting beads—2: methods for evaluating drug elution and in-vitro:in-vivo correlation

DC Bead™ is a sulfonate-modified, PVA-based microspherical embolisation agent approved for the treatment of hypervascular tumours and arterio-venous malformations. The beads have previously been shown to actively sequester oppositely charged drugs, such as doxorubicin hydrochloride (dox) by an ion-e...

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Veröffentlicht in:	Journal of materials science. Materials in medicine 2008-02, Vol.19 (2), p.767-775
Hauptverfasser:	Gonzalez, M. Victoria, Tang, Yiqing, Phillips, Gary J., Lloyd, Andrew W., Hall, Brenda, Stratford, Peter W., Lewis, Andrew L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics, Antineoplastic - administration & dosage Area Under Curve Biomaterials Biomedical Engineering and Bioengineering Biomedical materials Ceramics Chemistry and Materials Science Chemoembolization, Therapeutic - instrumentation Composites Delayed-Action Preparations Diffusion Dose-Response Relationship, Drug Doxorubicin - administration & dosage Doxorubicin - pharmacokinetics Drug delivery systems Drug Delivery Systems - instrumentation Glass Humans Materials Science Microspheres Natural Materials Neoplasms - drug therapy Polymer Sciences Polyvinyl Alcohol Regenerative Medicine/Tissue Engineering Studies Surfaces and Interfaces Thin Films Tumors
Online-Zugang:	Volltext
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