Crystal structure of the multifunctional Gbeta5-RGS9 complex

Regulators of G-protein signaling (RGS) proteins enhance the intrinsic GTPase activity of G protein alpha (Galpha) subunits and are vital for proper signaling kinetics downstream of G protein-coupled receptors (GPCRs). R7 subfamily RGS proteins specifically and obligately dimerize with the atypical...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nature structural & molecular biology 2008-02, Vol.15 (2), p.155-162
Hauptverfasser:	Cheever, Matthew L, Snyder, Jason T, Gershburg, Svetlana, Siderovski, David P, Harden, T Kendall, Sondek, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Crystallography, X-Ray Dimerization GTP-Binding Protein beta Subunits - chemistry Humans Models, Molecular Protein Binding Protein Structure, Quaternary Protein Structure, Tertiary RGS Proteins - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!