What is the role of adjuvant radiotherapy in the treatment of cutaneous squamous cell carcinoma with perineural invasion?

BACKGROUND. Perineural invasion (PNI) in cutaneous squamous cell carcinoma (SCC) is infrequent, occurring in 2.5% to 14% of patients, but it is important prognostically, because it carries an increased risk of recurrence and metastasis. Although both excision and Mohs micrographic surgery (MMS) are...

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Veröffentlicht in:	Cancer 2007-03, Vol.109 (6), p.1053-1059
Hauptverfasser:	Han, Anne, Ratner, Désireé
Format:	Artikel
Sprache:	eng
Schlagworte:	adjuvant radiotherapy Biological and medical sciences Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - radiotherapy Carcinoma, Squamous Cell - secondary Dermatology Humans Medical sciences Mohs micrographic surgery Neoplasm Invasiveness perineural invasion Peripheral Nerves - pathology Peripheral Nervous System Neoplasms - pathology Peripheral Nervous System Neoplasms - radiotherapy Radiotherapy, Adjuvant Skin Neoplasms - pathology Skin Neoplasms - radiotherapy squamous cell carcinoma Tumors Tumors of the skin and soft tissue. Premalignant lesions
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