Suspected Herpes Encephalitis and Opercular Syndrome in Childhood

Herpes simplex encephalitis is the most common form of sporadic viral encephalitis. It may occur at any age, giving rise to a syndrome with a high morbidity and mortality. Its presentation may be atypical, and the initial complementary investigations nonspecific, making early diagnosis difficult and...

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Veröffentlicht in:Pediatric neurology 2007-03, Vol.36 (3), p.202-206
Hauptverfasser: García-Ribes, Ainhoa, MD, Martínez-González, María Jesús, MD, Prats-Viñas, Jose María, MD
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container_title Pediatric neurology
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creator García-Ribes, Ainhoa, MD
Martínez-González, María Jesús, MD
Prats-Viñas, Jose María, MD
description Herpes simplex encephalitis is the most common form of sporadic viral encephalitis. It may occur at any age, giving rise to a syndrome with a high morbidity and mortality. Its presentation may be atypical, and the initial complementary investigations nonspecific, making early diagnosis difficult and thus worsening its prognosis. This report describes four infants with herpes encephalitis presenting with an opercular syndrome that left significant sequelae after the acute episode. The opercular syndrome is characterized clinically by a disturbance of voluntary control of the facio-linguo-glosso-pharyngeal muscles, affecting speech and swallowing. Recognition of the opercular syndrome as a form of presentation of herpes encephalitis enables early diagnosis to be made in these patients, with the rapid initiation of treatment with acyclovir, improving the clinical course.
doi_str_mv 10.1016/j.pediatrneurol.2006.10.006
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subjects Biological and medical sciences
Encephalitis, Herpes Simplex - complications
Encephalitis, Herpes Simplex - diagnosis
Encephalitis, Herpes Simplex - therapy
Female
Human viral diseases
Humans
Infant
Infant, Newborn
Infectious diseases
Male
Masticatory Muscles
Medical sciences
Movement Disorders - virology
Neurology
Pediatrics
Syndrome
Viral diseases
Viral diseases of the nervous system
Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
title Suspected Herpes Encephalitis and Opercular Syndrome in Childhood
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