Microdialysis-based analysis of interstitial NO in situ : NO synthase-independent NO formation during myocardial ischemia
Nitric oxide (NO) synthesis by NO synthases (NOS) requires oxygen. However, although counterintuitive, NO synthesis is increased in ischemic myocardium. Accordingly, mechanisms independent of the NOS pathway have been suggested to contribute to NO synthesis during ischemia. NO initiates detrimental...
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Veröffentlicht in: | Cardiovascular research 2007-04, Vol.74 (1), p.46-55 |
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