NSAIDs and Alzheimer disease: Epidemiological, animal model and clinical studies

Abstract This review reports correlations between four independent fields related to inflammation and Alzheimer disease: fundamental pathology, epidemiology, transgenic animal studies and clinical trials. Activated microglia, along with a spectrum of inflammatory mediators, have been identified in a...

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Veröffentlicht in:	Neurobiology of aging 2007-05, Vol.28 (5), p.639-647
Hauptverfasser:	McGeer, Patrick L, McGeer, Edith G
Format:	Artikel
Sprache:	eng
Schlagworte:	Activated microglia Alzheimer Disease - drug therapy Alzheimer Disease - epidemiology Amyloid Animals Anti-Inflammatory Agents, Non-Steroidal - therapeutic use COX-1 COX-2 Disease Models, Animal Humans Inflammation Internal Medicine Neurofibrillary tangles Neurology Transgenic mice
Online-Zugang:	Volltext
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