Human Kallikrein-related Peptidase 14 (KLK14) Is a New Activator Component of the KLK Proteolytic Cascade: POSSIBLE FUNCTION IN SEMINAL PLASMA AND SKIN

Human kallikrein-related peptidases (KLKs) are a family of 15 serine proteases mainly known for their biomarker utility in various neoplastic and non-neoplastic diseases. Despite significant progress in understanding their clinical application, little is known about the activation mechanism(s) of th...

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Veröffentlicht in:	The Journal of biological chemistry 2008-02, Vol.283 (6), p.3031-3041
Hauptverfasser:	Emami, Nashmil, Diamandis, Eleftherios P
Format:	Artikel
Sprache:	eng
Schlagworte:	Endopeptidases - chemistry Gene Expression Regulation Humans Kallikreins - chemistry Kallikreins - physiology Male Peptide Library Protein Binding Protein Processing, Post-Translational Recombinant Proteins - chemistry Semen - metabolism Serine Endopeptidases - chemistry Skin - metabolism Time Factors Trypsin - chemistry
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