Identification, synthesis, and biological evaluation of novel pyrazoles as low molecular weight luteinizing hormone receptor agonists

The synthesis and structure–activity relationship of pyrazole derivatives are described as novel low molecular weight LH-receptor agonists. In the course of a high throughput screening, a series of pyrazole compounds were identified with luteinizing hormone receptor (LH-R) agonist activity. A focuse...

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Veröffentlicht in:Bioorganic & medicinal chemistry letters 2007-04, Vol.17 (7), p.2080-2085
Hauptverfasser: Jorand-Lebrun, Catherine, Brondyk, Bill, Lin, Jing, Magar, Sharad, Murray, Robert, Reddy, Adulla, Shroff, Hitesh, Wands, Greg, Weiser, Weishui, Xu, Qihong, McKenna, Sean, Brugger, Nadia
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Sprache:eng
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