Pituitary tumors in children: clinical analysis of 21 cases
The aim of this study is to review the results of surgery for pituitary adenomas in children less than 18 years old. A retrospective review was done of pituitary adenoma patients with the age of less than 18 years who were treated in the period 1979-2003 at Dr. Shariati Hospital. Twenty-one patients...
Gespeichert in:
| Veröffentlicht in: | Child's nervous system 2007-04, Vol.23 (4), p.391-398 |
|---|---|
| 1. Verfasser: | |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 398 |
|---|---|
| container_issue | 4 |
| container_start_page | 391 |
| container_title | Child's nervous system |
| container_volume | 23 |
| creator | Mehrazin, M |
| description | The aim of this study is to review the results of surgery for pituitary adenomas in children less than 18 years old.
A retrospective review was done of pituitary adenoma patients with the age of less than 18 years who were treated in the period 1979-2003 at Dr. Shariati Hospital.
Twenty-one patients (12 girls and 9 boys) were identified. The age range (mean) in girls and boys was 9-18 (15.8) and 9-17 (14.8) years, respectively. The duration of follow-up was 1-23 (13.4) years. Eight patients (38.1%) had adrenocorticotropic hormone-secreting tumors, 33.3% had prolactin-secreting tumors, 19% had growth hormone-secreting tumors, and 9.53% had nonfunctioning adenomas. Multidisciplinary management included surgery and, if necessary, reoperation with/without radiotherapy and pharmacotherapy. Eleven patients, mostly with prolactinomas, acromegaly, and nonfunctioning adenomas, needed reoperation and radiotherapy. There were two deaths, one of which was because of apoplexy. The biological behavior of pediatric pituitary adenomas seems more aggressive than adults' adenomas. The chance of pituitary apoplexy in pediatric invasive pituitary adenoma is high. |
| doi_str_mv | 10.1007/s00381-006-0259-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70253649</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>70253649</sourcerecordid><originalsourceid>FETCH-LOGICAL-c365t-7733489060d728c81102a600d23e9382376f5dd502915e779cbd1ef07f4840b63</originalsourceid><addsrcrecordid>eNpFkEtLAzEUhYMotlZ_gBvJyl305jHJRFdSfEFBF7oOaZLBSGamTmYW_fdNacHVhcs5B74PoWsKdxRA3WcAXlMCIAmwShNxguZUcE6AV3CK5uUpiQIBM3SR8y8ArWqmz9GMqhKTgs_R42ccpzjaYYvHqe2HjGOH3U9MfgjdA3YpdtHZhG1n0zbHjPsGM4qdzSFforPGphyujneBvl-ev5ZvZPXx-r58WhHHZTUSpTgXtQYJXrHa1ZQCsxLAMx40rxlXsqm8r4BpWgWltFt7GhpQjagFrCVfoNvD7mbo_6aQR9PG7EJKtgv9lI0qnIVGlyA9BN3Q5zyExmyG2BY2Q8HsjZmDMVOMmb0xI0rn5jg-rdvg_xtHRXwHhT1j2g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70253649</pqid></control><display><type>article</type><title>Pituitary tumors in children: clinical analysis of 21 cases</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Mehrazin, M</creator><creatorcontrib>Mehrazin, M</creatorcontrib><description>The aim of this study is to review the results of surgery for pituitary adenomas in children less than 18 years old.
A retrospective review was done of pituitary adenoma patients with the age of less than 18 years who were treated in the period 1979-2003 at Dr. Shariati Hospital.
Twenty-one patients (12 girls and 9 boys) were identified. The age range (mean) in girls and boys was 9-18 (15.8) and 9-17 (14.8) years, respectively. The duration of follow-up was 1-23 (13.4) years. Eight patients (38.1%) had adrenocorticotropic hormone-secreting tumors, 33.3% had prolactin-secreting tumors, 19% had growth hormone-secreting tumors, and 9.53% had nonfunctioning adenomas. Multidisciplinary management included surgery and, if necessary, reoperation with/without radiotherapy and pharmacotherapy. Eleven patients, mostly with prolactinomas, acromegaly, and nonfunctioning adenomas, needed reoperation and radiotherapy. There were two deaths, one of which was because of apoplexy. The biological behavior of pediatric pituitary adenomas seems more aggressive than adults' adenomas. The chance of pituitary apoplexy in pediatric invasive pituitary adenoma is high.</description><identifier>ISSN: 0256-7040</identifier><identifier>EISSN: 1433-0350</identifier><identifier>DOI: 10.1007/s00381-006-0259-4</identifier><identifier>PMID: 17143643</identifier><language>eng</language><publisher>Germany</publisher><subject>Adenoma ; Adolescent ; Adrenocorticotropic Hormone ; Child ; Female ; Follow-Up Studies ; Humans ; Hypophysectomy ; Magnetic Resonance Imaging ; Male ; Pituitary Neoplasms - classification ; Pituitary Neoplasms - epidemiology ; Pituitary Neoplasms - pathology ; Pituitary Neoplasms - surgery ; Prolactinoma ; Retrospective Studies ; Severity of Illness Index ; Time Factors</subject><ispartof>Child's nervous system, 2007-04, Vol.23 (4), p.391-398</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c365t-7733489060d728c81102a600d23e9382376f5dd502915e779cbd1ef07f4840b63</citedby><cites>FETCH-LOGICAL-c365t-7733489060d728c81102a600d23e9382376f5dd502915e779cbd1ef07f4840b63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17143643$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mehrazin, M</creatorcontrib><title>Pituitary tumors in children: clinical analysis of 21 cases</title><title>Child's nervous system</title><addtitle>Childs Nerv Syst</addtitle><description>The aim of this study is to review the results of surgery for pituitary adenomas in children less than 18 years old.
A retrospective review was done of pituitary adenoma patients with the age of less than 18 years who were treated in the period 1979-2003 at Dr. Shariati Hospital.
Twenty-one patients (12 girls and 9 boys) were identified. The age range (mean) in girls and boys was 9-18 (15.8) and 9-17 (14.8) years, respectively. The duration of follow-up was 1-23 (13.4) years. Eight patients (38.1%) had adrenocorticotropic hormone-secreting tumors, 33.3% had prolactin-secreting tumors, 19% had growth hormone-secreting tumors, and 9.53% had nonfunctioning adenomas. Multidisciplinary management included surgery and, if necessary, reoperation with/without radiotherapy and pharmacotherapy. Eleven patients, mostly with prolactinomas, acromegaly, and nonfunctioning adenomas, needed reoperation and radiotherapy. There were two deaths, one of which was because of apoplexy. The biological behavior of pediatric pituitary adenomas seems more aggressive than adults' adenomas. The chance of pituitary apoplexy in pediatric invasive pituitary adenoma is high.</description><subject>Adenoma</subject><subject>Adolescent</subject><subject>Adrenocorticotropic Hormone</subject><subject>Child</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Hypophysectomy</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Pituitary Neoplasms - classification</subject><subject>Pituitary Neoplasms - epidemiology</subject><subject>Pituitary Neoplasms - pathology</subject><subject>Pituitary Neoplasms - surgery</subject><subject>Prolactinoma</subject><subject>Retrospective Studies</subject><subject>Severity of Illness Index</subject><subject>Time Factors</subject><issn>0256-7040</issn><issn>1433-0350</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEtLAzEUhYMotlZ_gBvJyl305jHJRFdSfEFBF7oOaZLBSGamTmYW_fdNacHVhcs5B74PoWsKdxRA3WcAXlMCIAmwShNxguZUcE6AV3CK5uUpiQIBM3SR8y8ArWqmz9GMqhKTgs_R42ccpzjaYYvHqe2HjGOH3U9MfgjdA3YpdtHZhG1n0zbHjPsGM4qdzSFforPGphyujneBvl-ev5ZvZPXx-r58WhHHZTUSpTgXtQYJXrHa1ZQCsxLAMx40rxlXsqm8r4BpWgWltFt7GhpQjagFrCVfoNvD7mbo_6aQR9PG7EJKtgv9lI0qnIVGlyA9BN3Q5zyExmyG2BY2Q8HsjZmDMVOMmb0xI0rn5jg-rdvg_xtHRXwHhT1j2g</recordid><startdate>20070401</startdate><enddate>20070401</enddate><creator>Mehrazin, M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070401</creationdate><title>Pituitary tumors in children: clinical analysis of 21 cases</title><author>Mehrazin, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-7733489060d728c81102a600d23e9382376f5dd502915e779cbd1ef07f4840b63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adenoma</topic><topic>Adolescent</topic><topic>Adrenocorticotropic Hormone</topic><topic>Child</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Hypophysectomy</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Pituitary Neoplasms - classification</topic><topic>Pituitary Neoplasms - epidemiology</topic><topic>Pituitary Neoplasms - pathology</topic><topic>Pituitary Neoplasms - surgery</topic><topic>Prolactinoma</topic><topic>Retrospective Studies</topic><topic>Severity of Illness Index</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mehrazin, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Child's nervous system</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mehrazin, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pituitary tumors in children: clinical analysis of 21 cases</atitle><jtitle>Child's nervous system</jtitle><addtitle>Childs Nerv Syst</addtitle><date>2007-04-01</date><risdate>2007</risdate><volume>23</volume><issue>4</issue><spage>391</spage><epage>398</epage><pages>391-398</pages><issn>0256-7040</issn><eissn>1433-0350</eissn><abstract>The aim of this study is to review the results of surgery for pituitary adenomas in children less than 18 years old.
A retrospective review was done of pituitary adenoma patients with the age of less than 18 years who were treated in the period 1979-2003 at Dr. Shariati Hospital.
Twenty-one patients (12 girls and 9 boys) were identified. The age range (mean) in girls and boys was 9-18 (15.8) and 9-17 (14.8) years, respectively. The duration of follow-up was 1-23 (13.4) years. Eight patients (38.1%) had adrenocorticotropic hormone-secreting tumors, 33.3% had prolactin-secreting tumors, 19% had growth hormone-secreting tumors, and 9.53% had nonfunctioning adenomas. Multidisciplinary management included surgery and, if necessary, reoperation with/without radiotherapy and pharmacotherapy. Eleven patients, mostly with prolactinomas, acromegaly, and nonfunctioning adenomas, needed reoperation and radiotherapy. There were two deaths, one of which was because of apoplexy. The biological behavior of pediatric pituitary adenomas seems more aggressive than adults' adenomas. The chance of pituitary apoplexy in pediatric invasive pituitary adenoma is high.</abstract><cop>Germany</cop><pmid>17143643</pmid><doi>10.1007/s00381-006-0259-4</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0256-7040 |
| ispartof | Child's nervous system, 2007-04, Vol.23 (4), p.391-398 |
| issn | 0256-7040 1433-0350 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70253649 |
| source | MEDLINE; SpringerNature Journals |
| subjects | Adenoma Adolescent Adrenocorticotropic Hormone Child Female Follow-Up Studies Humans Hypophysectomy Magnetic Resonance Imaging Male Pituitary Neoplasms - classification Pituitary Neoplasms - epidemiology Pituitary Neoplasms - pathology Pituitary Neoplasms - surgery Prolactinoma Retrospective Studies Severity of Illness Index Time Factors |
| title | Pituitary tumors in children: clinical analysis of 21 cases |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T03%3A41%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pituitary%20tumors%20in%20children:%20clinical%20analysis%20of%2021%20cases&rft.jtitle=Child's%20nervous%20system&rft.au=Mehrazin,%20M&rft.date=2007-04-01&rft.volume=23&rft.issue=4&rft.spage=391&rft.epage=398&rft.pages=391-398&rft.issn=0256-7040&rft.eissn=1433-0350&rft_id=info:doi/10.1007/s00381-006-0259-4&rft_dat=%3Cproquest_cross%3E70253649%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=70253649&rft_id=info:pmid/17143643&rfr_iscdi=true |