Outcomes for COPD pharmacological trials: from lung function to biomarkers

The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current o...

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Veröffentlicht in:The European respiratory journal 2008-02, Vol.31 (2), p.416-469
Hauptverfasser: Cazzola, M, MacNee, W, Martinez, F. J, Rabe, K. F, Franciosi, L. G, Barnes, P. J, Brusasco, V, Burge, P. S, Calverley, P. M. A, Celli, B. R, Jones, P. W, Mahler, D. A, Make, B, Miravitlles, M, Page, C. P, Palange, P, Parr, D, Pistolesi, M, Rennard, S. I, Rutten-van Molken, M. P, Stockley, R, Sullivan, S. D, Wedzicha, J. A, Wouters, E. F, on behalf of American Thoracic Society/European Respiratory Society Task Force on outcomes of COPD
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Sprache:eng
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Zusammenfassung:The American Thoracic Society/European Respiratory Society jointly created a Task Force on "Outcomes for COPD pharmacological trials: from lung function to biomarkers" to inform the chronic obstructive pulmonary disease research community about the possible use and limitations of current outcomes and markers when evaluating the impact of a pharmacological therapy. Based on their review of the published literature, the following document has been prepared with individual sections that address specific outcomes and markers, and a final section that summarises their recommendations.
ISSN:0903-1936
1399-3003
DOI:10.1183/09031936.00099306