Changes in the Brain Serotonin Satiety System in Transgenic Rats Lacking Brain Angiotensinogen

In transgenic rats, TGR(ASrAOGEN)680, with reduced glial expression of angiotensinogen, changes in brain angiotensinogen are associated with reductions in serotonin (5‐HT) content and/or 5‐HT metabolism as determined in various brain regions, including the hypothalamus. These rats showed an anxious...

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Veröffentlicht in:	Journal of neuroendocrinology 2008-02, Vol.20 (2), p.182-187
Hauptverfasser:	Voigt, J.-P., Raasch, W., Hörtnagl, H., Bader, M., Fink, H., Jöhren, O.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT 5-HT receptor expression 5-HTT expression Angiotensinogen - deficiency Animals Animals, Genetically Modified Biological and medical sciences Body Weight Brain - metabolism Brain - physiology Cerebral Cortex - metabolism Eating - drug effects Feeding Behavior - physiology fenfluramine Fenfluramine - pharmacology Fundamental and applied biological sciences. Psychology hypothalamus Hypothalamus - metabolism Male Rats Rats, Sprague-Dawley Receptors, Serotonin - genetics RNA, Messenger - metabolism Satiety Response - drug effects Satiety Response - physiology Serotonin - pharmacology Serotonin - physiology Serotonin Agents - pharmacology Serotonin Plasma Membrane Transport Proteins - genetics Vertebrates: endocrinology
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