Updates in the Management of Gout
Abstract The majority of patients with gout are cared for by primary care physicians. Although both the physician and patient may easily recognize the acute arthritis of gout, errors in selecting the most appropriate medication and proper dose are common. The clinical stages of gout include asymptom...
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| Veröffentlicht in: | The American journal of medicine 2007-03, Vol.120 (3), p.221-224 |
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| creator | Keith, Michael P., MD Gilliland, William R., MD, MHPE |
| description | Abstract The majority of patients with gout are cared for by primary care physicians. Although both the physician and patient may easily recognize the acute arthritis of gout, errors in selecting the most appropriate medication and proper dose are common. The clinical stages of gout include asymptomatic hyperuricemia, intermittent gouty arthritis, and chronic tophaceous gout. Treatment of gout is usually considered after the first attack of arthritis, typically podagra. The aims of treatment are to alleviate the pain and inflammation associated with acute attacks, prevent future attacks, and decrease uric acid levels. Confusion frequently arises because certain medications such as colchicine may have dual purposes: to treat an acute attack and to suppress future attacks. The purpose of this management update is to provide practical advice about prescribing the proper medication considering both treatment goals and patient comorbidities. |
| doi_str_mv | 10.1016/j.amjmed.2006.02.044 |
| format | Article |
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Although both the physician and patient may easily recognize the acute arthritis of gout, errors in selecting the most appropriate medication and proper dose are common. The clinical stages of gout include asymptomatic hyperuricemia, intermittent gouty arthritis, and chronic tophaceous gout. Treatment of gout is usually considered after the first attack of arthritis, typically podagra. The aims of treatment are to alleviate the pain and inflammation associated with acute attacks, prevent future attacks, and decrease uric acid levels. Confusion frequently arises because certain medications such as colchicine may have dual purposes: to treat an acute attack and to suppress future attacks. The purpose of this management update is to provide practical advice about prescribing the proper medication considering both treatment goals and patient comorbidities.</description><identifier>ISSN: 0002-9343</identifier><identifier>EISSN: 1555-7162</identifier><identifier>DOI: 10.1016/j.amjmed.2006.02.044</identifier><identifier>PMID: 17349440</identifier><identifier>CODEN: AJMEAZ</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Acute Disease ; Adrenal Cortex Hormones - therapeutic use ; Adult ; Aged ; Allopurinol - therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use ; Arthritis, Gouty - diagnosis ; Arthritis, Gouty - drug therapy ; Biological and medical sciences ; Chronic Disease ; Colchicine ; Colchicine - therapeutic use ; Disease management ; Drug therapy ; Drug Therapy, Combination ; Family Practice - standards ; Family Practice - trends ; Febuxostat ; Female ; General aspects ; Gout ; Gout - diagnosis ; Gout - drug therapy ; Gout Suppressants - therapeutic use ; Humans ; Inflammatory diseases ; Internal Medicine ; Male ; Management ; Medical sciences ; Medical treatment ; Metabolic diseases ; Middle Aged ; Miscellaneous ; Nonsteroidal anti-inflammatory agents ; Other metabolic disorders ; Pain management ; Pain Measurement ; Primary care ; Probenecid ; Prognosis ; Rheumatism ; Risk Assessment ; Severity of Illness Index ; Treatment Outcome ; Uric Acid - urine ; Xanthine oxidase</subject><ispartof>The American journal of medicine, 2007-03, Vol.120 (3), p.221-224</ispartof><rights>Elsevier Inc.</rights><rights>2007 Elsevier Inc.</rights><rights>2007 INIST-CNRS</rights><rights>Copyright Elsevier Sequoia S.A. 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Although both the physician and patient may easily recognize the acute arthritis of gout, errors in selecting the most appropriate medication and proper dose are common. The clinical stages of gout include asymptomatic hyperuricemia, intermittent gouty arthritis, and chronic tophaceous gout. Treatment of gout is usually considered after the first attack of arthritis, typically podagra. The aims of treatment are to alleviate the pain and inflammation associated with acute attacks, prevent future attacks, and decrease uric acid levels. Confusion frequently arises because certain medications such as colchicine may have dual purposes: to treat an acute attack and to suppress future attacks. The purpose of this management update is to provide practical advice about prescribing the proper medication considering both treatment goals and patient comorbidities.</description><subject>Acute Disease</subject><subject>Adrenal Cortex Hormones - therapeutic use</subject><subject>Adult</subject><subject>Aged</subject><subject>Allopurinol - therapeutic use</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</subject><subject>Arthritis, Gouty - diagnosis</subject><subject>Arthritis, Gouty - drug therapy</subject><subject>Biological and medical sciences</subject><subject>Chronic Disease</subject><subject>Colchicine</subject><subject>Colchicine - therapeutic use</subject><subject>Disease management</subject><subject>Drug therapy</subject><subject>Drug Therapy, Combination</subject><subject>Family Practice - standards</subject><subject>Family Practice - trends</subject><subject>Febuxostat</subject><subject>Female</subject><subject>General aspects</subject><subject>Gout</subject><subject>Gout - diagnosis</subject><subject>Gout - drug therapy</subject><subject>Gout Suppressants - therapeutic use</subject><subject>Humans</subject><subject>Inflammatory diseases</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Management</subject><subject>Medical sciences</subject><subject>Medical treatment</subject><subject>Metabolic diseases</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Nonsteroidal anti-inflammatory agents</subject><subject>Other metabolic disorders</subject><subject>Pain management</subject><subject>Pain Measurement</subject><subject>Primary care</subject><subject>Probenecid</subject><subject>Prognosis</subject><subject>Rheumatism</subject><subject>Risk Assessment</subject><subject>Severity of Illness Index</subject><subject>Treatment Outcome</subject><subject>Uric Acid - urine</subject><subject>Xanthine oxidase</subject><issn>0002-9343</issn><issn>1555-7162</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1v1DAQhi1ERZfCP0AoIMEtYezY3vhSCVVQKhX1UHq2Zu0JOORjsROk_nscdlWkXpAPluVnXo-fYewVh4oD1x-6CoduIF8JAF2BqEDKJ2zDlVLllmvxlG0AQJSmlvUpe55Sl49glH7GTvm2lkZK2LA3d3uPM6UijMX8g4qvOOJ3Gmici6ktLqdlfsFOWuwTvTzuZ-zu86dvF1_K65vLq4uP16WTpplLwsYgeK1IoWtVI5sGUJMHDl7uHKIHMhp9TWZXK0VbJVG3Sta0U1o1uj5j7w-5-zj9WijNdgjJUd_jSNOS7BaEzKFNBt8-ArtpiWPuzYr67zIyQ_IAuTilFKm1-xgGjPeWg1392c4e_NnVnwVhs79c9vqYvezWu4eio7AMvDsCmBz2bcTRhfSPawwXRojMnR84ysp-B4o2uUCjIx8iudn6Kfyvk8cBrg9jyG_-pHtKD1_mNuUCe7vOeh01aAAFStV_ABzqocs</recordid><startdate>20070301</startdate><enddate>20070301</enddate><creator>Keith, Michael P., MD</creator><creator>Gilliland, William R., MD, MHPE</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Sequoia S.A</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7TO</scope><scope>7TS</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>20070301</creationdate><title>Updates in the Management of Gout</title><author>Keith, Michael P., MD ; Gilliland, William R., MD, MHPE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c498t-ea89a0d65e5acf584880a6ed010d4bcaad0e96ad3e9b355e754a6f543eb565863</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Acute Disease</topic><topic>Adrenal Cortex Hormones - therapeutic use</topic><topic>Adult</topic><topic>Aged</topic><topic>Allopurinol - therapeutic use</topic><topic>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</topic><topic>Arthritis, Gouty - diagnosis</topic><topic>Arthritis, Gouty - drug therapy</topic><topic>Biological and medical sciences</topic><topic>Chronic Disease</topic><topic>Colchicine</topic><topic>Colchicine - therapeutic use</topic><topic>Disease management</topic><topic>Drug therapy</topic><topic>Drug Therapy, Combination</topic><topic>Family Practice - standards</topic><topic>Family Practice - trends</topic><topic>Febuxostat</topic><topic>Female</topic><topic>General aspects</topic><topic>Gout</topic><topic>Gout - diagnosis</topic><topic>Gout - drug therapy</topic><topic>Gout Suppressants - therapeutic use</topic><topic>Humans</topic><topic>Inflammatory diseases</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Management</topic><topic>Medical sciences</topic><topic>Medical treatment</topic><topic>Metabolic diseases</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Nonsteroidal anti-inflammatory agents</topic><topic>Other metabolic disorders</topic><topic>Pain management</topic><topic>Pain Measurement</topic><topic>Primary care</topic><topic>Probenecid</topic><topic>Prognosis</topic><topic>Rheumatism</topic><topic>Risk Assessment</topic><topic>Severity of Illness Index</topic><topic>Treatment Outcome</topic><topic>Uric Acid - urine</topic><topic>Xanthine oxidase</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Keith, Michael P., MD</creatorcontrib><creatorcontrib>Gilliland, William R., MD, MHPE</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Physical Education Index</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Keith, Michael P., MD</au><au>Gilliland, William R., MD, MHPE</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Updates in the Management of Gout</atitle><jtitle>The American journal of medicine</jtitle><addtitle>Am J Med</addtitle><date>2007-03-01</date><risdate>2007</risdate><volume>120</volume><issue>3</issue><spage>221</spage><epage>224</epage><pages>221-224</pages><issn>0002-9343</issn><eissn>1555-7162</eissn><coden>AJMEAZ</coden><abstract>Abstract The majority of patients with gout are cared for by primary care physicians. Although both the physician and patient may easily recognize the acute arthritis of gout, errors in selecting the most appropriate medication and proper dose are common. The clinical stages of gout include asymptomatic hyperuricemia, intermittent gouty arthritis, and chronic tophaceous gout. Treatment of gout is usually considered after the first attack of arthritis, typically podagra. The aims of treatment are to alleviate the pain and inflammation associated with acute attacks, prevent future attacks, and decrease uric acid levels. Confusion frequently arises because certain medications such as colchicine may have dual purposes: to treat an acute attack and to suppress future attacks. The purpose of this management update is to provide practical advice about prescribing the proper medication considering both treatment goals and patient comorbidities.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17349440</pmid><doi>10.1016/j.amjmed.2006.02.044</doi><tpages>4</tpages></addata></record> |
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| subjects | Acute Disease Adrenal Cortex Hormones - therapeutic use Adult Aged Allopurinol - therapeutic use Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Arthritis, Gouty - diagnosis Arthritis, Gouty - drug therapy Biological and medical sciences Chronic Disease Colchicine Colchicine - therapeutic use Disease management Drug therapy Drug Therapy, Combination Family Practice - standards Family Practice - trends Febuxostat Female General aspects Gout Gout - diagnosis Gout - drug therapy Gout Suppressants - therapeutic use Humans Inflammatory diseases Internal Medicine Male Management Medical sciences Medical treatment Metabolic diseases Middle Aged Miscellaneous Nonsteroidal anti-inflammatory agents Other metabolic disorders Pain management Pain Measurement Primary care Probenecid Prognosis Rheumatism Risk Assessment Severity of Illness Index Treatment Outcome Uric Acid - urine Xanthine oxidase |
| title | Updates in the Management of Gout |
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