$Biologically Active Aspidofractinine Alkaloids from Kopsia singapurensis$

Biologically Active Aspidofractinine Alkaloids from Kopsia singapurensis

Ten new indole alkaloids of the aspidofractinine type, in addition to several recently reported indole alkaloids and 20 other known alkaloids, were obtained from the leaf and stem-bark extract of the Malayan Kopsia singapurensis, viz., kopsimalines A−E (1−5), kopsinicine (6), kopsofinone (7), and ko...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2008-01, Vol.71 (1), p.53-57
Hauptverfasser:	Subramaniam, G, Hiraku, Osamu, Hayashi, Masahiko, Koyano, Takashi, Komiyama, Kanki, Kam, Toh-Seok
Format:	Artikel
Sprache:	eng
Schlagworte:	anticarcinogenic activity Antineoplastic Agents, Phytogenic - chemistry Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Apocynaceae Apocynaceae - chemistry aspidofractinine alkaloids Biological and medical sciences chemical structure cultured cells cytotoxicity Drug Resistance, Neoplasm - drug effects Drug Screening Assays, Antitumor General pharmacology Humans indole alkaloids Indole Alkaloids - chemistry Indole Alkaloids - isolation & purification Indole Alkaloids - pharmacology KB Cells Kopsia singapurensis kopsiloscine kopsimaline kopsinicine kopsofinone Malaysia Medical sciences Molecular Structure multiple drug resistance Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Bark - chemistry Plant Leaves - chemistry Plants, Medicinal - chemistry spectral analysis Vincristine - pharmacology
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