Plasmodium falciparum—Infected Erythrocytes Decrease the Integrity of Human Blood-Brain Barrier Endothelial Cell Monolayers

Background. Central to the pathologic progression of human cerebral malaria (CM) is sequestration of Plasmodium falciparum—infected red blood cells (Pf-IRBCs) to the blood-brain barrier (BBB) endothelium. The molecular interactions between Pf-IRBCs and the BBB endothelium and their implications for...

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Veröffentlicht in:	The Journal of infectious diseases 2007-04, Vol.195 (7), p.942-950
Hauptverfasser:	Tripathi, Abhai K., Sullivan, David J., Stins, Monique F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood brain barrier Blood-Brain Barrier - physiology Brain - parasitology Cerebral malaria Electric Impedance Electrical resistance Endothelial cells Endothelium Endothelium, Vascular - cytology Endothelium, Vascular - parasitology Erythrocyte membrane Erythrocytes Erythrocytes - parasitology Humans Malaria Malaria, Cerebral - parasitology Parasites Parasitism Plasmodium falciparum - physiology
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