IgG anti-GalNAc-GD1a antibody inhibits the voltage-dependent calcium channel currents in PC12 pheochromocytoma cells

We investigated the effects of IgG anti-GalNAc-GD1a antibodies, produced by immunizing rabbits with GalNAc-GD1a, on the voltage-dependent calcium channel (VDCCs) currents in nerve growth factor (NGF)-differentiated PC12 pheochromocytoma cells. VDCCs currents in NGF-differentiated PC12 cells were rec...

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Veröffentlicht in:	Experimental neurology 2007-03, Vol.204 (1), p.380-386
Hauptverfasser:	Nakatani, Yoshihiko, Nagaoka, Takumi, Hotta, Sayako, Utsunomiya, Iku, Yoshino, Hiide, Miyatake, Tadashi, Hoshi, Keiko, Taguchi, Kyoji
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-GalNAc-GD1a antibodies Calcium Channels - drug effects Calcium Channels - metabolism Cell Differentiation Electric Conductivity Gangliosides - immunology Immunoglobulin G - pharmacology Immunologic Techniques Nerve Growth Factor - pharmacology PC12 Cells - metabolism PC12 Cells - pathology PC12 pheochromocytoma cells Peripheral nerves Rabbits Rats Staining and Labeling Voltage-dependent calcium channel currents
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