An Appraisal of “Chronic Lyme Disease”

To the Editor: Feder et al. (Oct. 4 issue) 1 review the great controversy surrounding “chronic Lyme disease.” For most patients with this diagnosis, the authors advocate against the use of antibiotics. But before the decision is made not to use antibiotics for patients with post–tick-bite symptoms,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The New England journal of medicine 2008-01, Vol.358 (4), p.428-431
Hauptverfasser: Mayer, Lawrence, Merz, Susanne
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 431
container_issue 4
container_start_page 428
container_title The New England journal of medicine
container_volume 358
creator Mayer, Lawrence
Merz, Susanne
description To the Editor: Feder et al. (Oct. 4 issue) 1 review the great controversy surrounding “chronic Lyme disease.” For most patients with this diagnosis, the authors advocate against the use of antibiotics. But before the decision is made not to use antibiotics for patients with post–tick-bite symptoms, anaplasma, babesia, bartonella, 2 and ehrlichia must be ruled out. These tick-borne 2 intracellular pathogens are difficult to diagnose and can establish long-term, persistent infection. 3 – 5 Anaplasma, babesia, and bartonella are underdiagnosed: the nonspecific symptoms of infections with these organisms tend to be ascribed to the more easily identifiable Lyme disease, which often accompanies them. 2 – . . .
doi_str_mv 10.1056/NEJMc073063
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70234383</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1417724211</sourcerecordid><originalsourceid>FETCH-LOGICAL-c460t-bcf5e5e81527c61610e69b9fec12faefab47473e77777a25b210aa4221dddf6c3</originalsourceid><addsrcrecordid>eNqN0LtOwzAUBmALgWi5TOwoAokBFPCxHScZq1JuKrDAbDnOsUiVS7GboVsfBF6uT0KqVgIhBv7lLJ9-6fyEHAG9BBrJq6fRw6OhMaeSb5E-RJyHQlC5TfqUsiQUccp7ZM_7Ce0CIt0lPUgYSC6TPjkf1MFgOnW68LoMGhssFx_DN9fUhQnG8wqD68Kj9rhcfB6QHatLj4ebu09eb0Yvw7tw_Hx7PxyMQyMknYWZsRFGmEDEYiNBAkWZZqlFA8xqtDoTsYg5xqtoFmUMqNaCMcjz3ErD98nZunfqmvcW_UxVhTdYlrrGpvUqpowLnvB_Qc6E6ODJLzhpWld3TyjGeMoECOjQxRoZ13jv0KqpKyrt5gqoWg2tfgzd6eNNZZtVmH_bzbIdOF2DqvKqxkn1Z80XnXyBzA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>223924141</pqid></control><display><type>article</type><title>An Appraisal of “Chronic Lyme Disease”</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>New England Journal of Medicine</source><creator>Mayer, Lawrence ; Merz, Susanne</creator><creatorcontrib>Mayer, Lawrence ; Merz, Susanne</creatorcontrib><description>To the Editor: Feder et al. (Oct. 4 issue) 1 review the great controversy surrounding “chronic Lyme disease.” For most patients with this diagnosis, the authors advocate against the use of antibiotics. But before the decision is made not to use antibiotics for patients with post–tick-bite symptoms, anaplasma, babesia, bartonella, 2 and ehrlichia must be ruled out. These tick-borne 2 intracellular pathogens are difficult to diagnose and can establish long-term, persistent infection. 3 – 5 Anaplasma, babesia, and bartonella are underdiagnosed: the nonspecific symptoms of infections with these organisms tend to be ascribed to the more easily identifiable Lyme disease, which often accompanies them. 2 – . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMc073063</identifier><identifier>PMID: 18216368</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Anti-Bacterial Agents - therapeutic use ; Borrelia burgdorferi Group ; Chronic Disease ; Diagnosis, Differential ; Humans ; Lyme Disease - diagnosis ; Tick-Borne Diseases - diagnosis ; Tick-Borne Diseases - transmission</subject><ispartof>The New England journal of medicine, 2008-01, Vol.358 (4), p.428-431</ispartof><rights>Copyright © 2008 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c460t-bcf5e5e81527c61610e69b9fec12faefab47473e77777a25b210aa4221dddf6c3</citedby><cites>FETCH-LOGICAL-c460t-bcf5e5e81527c61610e69b9fec12faefab47473e77777a25b210aa4221dddf6c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMc073063$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJMc073063$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18216368$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mayer, Lawrence</creatorcontrib><creatorcontrib>Merz, Susanne</creatorcontrib><title>An Appraisal of “Chronic Lyme Disease”</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor: Feder et al. (Oct. 4 issue) 1 review the great controversy surrounding “chronic Lyme disease.” For most patients with this diagnosis, the authors advocate against the use of antibiotics. But before the decision is made not to use antibiotics for patients with post–tick-bite symptoms, anaplasma, babesia, bartonella, 2 and ehrlichia must be ruled out. These tick-borne 2 intracellular pathogens are difficult to diagnose and can establish long-term, persistent infection. 3 – 5 Anaplasma, babesia, and bartonella are underdiagnosed: the nonspecific symptoms of infections with these organisms tend to be ascribed to the more easily identifiable Lyme disease, which often accompanies them. 2 – . . .</description><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Borrelia burgdorferi Group</subject><subject>Chronic Disease</subject><subject>Diagnosis, Differential</subject><subject>Humans</subject><subject>Lyme Disease - diagnosis</subject><subject>Tick-Borne Diseases - diagnosis</subject><subject>Tick-Borne Diseases - transmission</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqN0LtOwzAUBmALgWi5TOwoAokBFPCxHScZq1JuKrDAbDnOsUiVS7GboVsfBF6uT0KqVgIhBv7lLJ9-6fyEHAG9BBrJq6fRw6OhMaeSb5E-RJyHQlC5TfqUsiQUccp7ZM_7Ce0CIt0lPUgYSC6TPjkf1MFgOnW68LoMGhssFx_DN9fUhQnG8wqD68Kj9rhcfB6QHatLj4ebu09eb0Yvw7tw_Hx7PxyMQyMknYWZsRFGmEDEYiNBAkWZZqlFA8xqtDoTsYg5xqtoFmUMqNaCMcjz3ErD98nZunfqmvcW_UxVhTdYlrrGpvUqpowLnvB_Qc6E6ODJLzhpWld3TyjGeMoECOjQxRoZ13jv0KqpKyrt5gqoWg2tfgzd6eNNZZtVmH_bzbIdOF2DqvKqxkn1Z80XnXyBzA</recordid><startdate>20080124</startdate><enddate>20080124</enddate><creator>Mayer, Lawrence</creator><creator>Merz, Susanne</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20080124</creationdate><title>An Appraisal of “Chronic Lyme Disease”</title><author>Mayer, Lawrence ; Merz, Susanne</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c460t-bcf5e5e81527c61610e69b9fec12faefab47473e77777a25b210aa4221dddf6c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Borrelia burgdorferi Group</topic><topic>Chronic Disease</topic><topic>Diagnosis, Differential</topic><topic>Humans</topic><topic>Lyme Disease - diagnosis</topic><topic>Tick-Borne Diseases - diagnosis</topic><topic>Tick-Borne Diseases - transmission</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mayer, Lawrence</creatorcontrib><creatorcontrib>Merz, Susanne</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mayer, Lawrence</au><au>Merz, Susanne</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An Appraisal of “Chronic Lyme Disease”</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2008-01-24</date><risdate>2008</risdate><volume>358</volume><issue>4</issue><spage>428</spage><epage>431</epage><pages>428-431</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>To the Editor: Feder et al. (Oct. 4 issue) 1 review the great controversy surrounding “chronic Lyme disease.” For most patients with this diagnosis, the authors advocate against the use of antibiotics. But before the decision is made not to use antibiotics for patients with post–tick-bite symptoms, anaplasma, babesia, bartonella, 2 and ehrlichia must be ruled out. These tick-borne 2 intracellular pathogens are difficult to diagnose and can establish long-term, persistent infection. 3 – 5 Anaplasma, babesia, and bartonella are underdiagnosed: the nonspecific symptoms of infections with these organisms tend to be ascribed to the more easily identifiable Lyme disease, which often accompanies them. 2 – . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>18216368</pmid><doi>10.1056/NEJMc073063</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0028-4793
ispartof The New England journal of medicine, 2008-01, Vol.358 (4), p.428-431
issn 0028-4793
1533-4406
language eng
recordid cdi_proquest_miscellaneous_70234383
source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine
subjects Anti-Bacterial Agents - therapeutic use
Borrelia burgdorferi Group
Chronic Disease
Diagnosis, Differential
Humans
Lyme Disease - diagnosis
Tick-Borne Diseases - diagnosis
Tick-Borne Diseases - transmission
title An Appraisal of “Chronic Lyme Disease”
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-02T02%3A11%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=An%20Appraisal%20of%20%E2%80%9CChronic%20Lyme%20Disease%E2%80%9D&rft.jtitle=The%20New%20England%20journal%20of%20medicine&rft.au=Mayer,%20Lawrence&rft.date=2008-01-24&rft.volume=358&rft.issue=4&rft.spage=428&rft.epage=431&rft.pages=428-431&rft.issn=0028-4793&rft.eissn=1533-4406&rft.coden=NEJMAG&rft_id=info:doi/10.1056/NEJMc073063&rft_dat=%3Cproquest_cross%3E1417724211%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=223924141&rft_id=info:pmid/18216368&rfr_iscdi=true