An Appraisal of “Chronic Lyme Disease”
To the Editor: Feder et al. (Oct. 4 issue) 1 review the great controversy surrounding “chronic Lyme disease.” For most patients with this diagnosis, the authors advocate against the use of antibiotics. But before the decision is made not to use antibiotics for patients with post–tick-bite symptoms,...
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Veröffentlicht in: | The New England journal of medicine 2008-01, Vol.358 (4), p.428-431 |
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container_title | The New England journal of medicine |
container_volume | 358 |
creator | Mayer, Lawrence Merz, Susanne |
description | To the Editor:
Feder et al. (Oct. 4 issue)
1
review the great controversy surrounding “chronic Lyme disease.” For most patients with this diagnosis, the authors advocate against the use of antibiotics.
But before the decision is made not to use antibiotics for patients with post–tick-bite symptoms, anaplasma, babesia, bartonella,
2
and ehrlichia must be ruled out. These tick-borne
2
intracellular pathogens are difficult to diagnose and can establish long-term, persistent infection.
3
–
5
Anaplasma, babesia, and bartonella are underdiagnosed: the nonspecific symptoms of infections with these organisms tend to be ascribed to the more easily identifiable Lyme disease, which often accompanies them.
2
– . . . |
doi_str_mv | 10.1056/NEJMc073063 |
format | Article |
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Feder et al. (Oct. 4 issue)
1
review the great controversy surrounding “chronic Lyme disease.” For most patients with this diagnosis, the authors advocate against the use of antibiotics.
But before the decision is made not to use antibiotics for patients with post–tick-bite symptoms, anaplasma, babesia, bartonella,
2
and ehrlichia must be ruled out. These tick-borne
2
intracellular pathogens are difficult to diagnose and can establish long-term, persistent infection.
3
–
5
Anaplasma, babesia, and bartonella are underdiagnosed: the nonspecific symptoms of infections with these organisms tend to be ascribed to the more easily identifiable Lyme disease, which often accompanies them.
2
– . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMc073063</identifier><identifier>PMID: 18216368</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Anti-Bacterial Agents - therapeutic use ; Borrelia burgdorferi Group ; Chronic Disease ; Diagnosis, Differential ; Humans ; Lyme Disease - diagnosis ; Tick-Borne Diseases - diagnosis ; Tick-Borne Diseases - transmission</subject><ispartof>The New England journal of medicine, 2008-01, Vol.358 (4), p.428-431</ispartof><rights>Copyright © 2008 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c460t-bcf5e5e81527c61610e69b9fec12faefab47473e77777a25b210aa4221dddf6c3</citedby><cites>FETCH-LOGICAL-c460t-bcf5e5e81527c61610e69b9fec12faefab47473e77777a25b210aa4221dddf6c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMc073063$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJMc073063$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18216368$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mayer, Lawrence</creatorcontrib><creatorcontrib>Merz, Susanne</creatorcontrib><title>An Appraisal of “Chronic Lyme Disease”</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
Feder et al. (Oct. 4 issue)
1
review the great controversy surrounding “chronic Lyme disease.” For most patients with this diagnosis, the authors advocate against the use of antibiotics.
But before the decision is made not to use antibiotics for patients with post–tick-bite symptoms, anaplasma, babesia, bartonella,
2
and ehrlichia must be ruled out. These tick-borne
2
intracellular pathogens are difficult to diagnose and can establish long-term, persistent infection.
3
–
5
Anaplasma, babesia, and bartonella are underdiagnosed: the nonspecific symptoms of infections with these organisms tend to be ascribed to the more easily identifiable Lyme disease, which often accompanies them.
2
– . . .</description><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Borrelia burgdorferi Group</subject><subject>Chronic Disease</subject><subject>Diagnosis, Differential</subject><subject>Humans</subject><subject>Lyme Disease - diagnosis</subject><subject>Tick-Borne Diseases - diagnosis</subject><subject>Tick-Borne Diseases - transmission</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqN0LtOwzAUBmALgWi5TOwoAokBFPCxHScZq1JuKrDAbDnOsUiVS7GboVsfBF6uT0KqVgIhBv7lLJ9-6fyEHAG9BBrJq6fRw6OhMaeSb5E-RJyHQlC5TfqUsiQUccp7ZM_7Ce0CIt0lPUgYSC6TPjkf1MFgOnW68LoMGhssFx_DN9fUhQnG8wqD68Kj9rhcfB6QHatLj4ebu09eb0Yvw7tw_Hx7PxyMQyMknYWZsRFGmEDEYiNBAkWZZqlFA8xqtDoTsYg5xqtoFmUMqNaCMcjz3ErD98nZunfqmvcW_UxVhTdYlrrGpvUqpowLnvB_Qc6E6ODJLzhpWld3TyjGeMoECOjQxRoZ13jv0KqpKyrt5gqoWg2tfgzd6eNNZZtVmH_bzbIdOF2DqvKqxkn1Z80XnXyBzA</recordid><startdate>20080124</startdate><enddate>20080124</enddate><creator>Mayer, Lawrence</creator><creator>Merz, Susanne</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20080124</creationdate><title>An Appraisal of “Chronic Lyme Disease”</title><author>Mayer, Lawrence ; 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Feder et al. (Oct. 4 issue)
1
review the great controversy surrounding “chronic Lyme disease.” For most patients with this diagnosis, the authors advocate against the use of antibiotics.
But before the decision is made not to use antibiotics for patients with post–tick-bite symptoms, anaplasma, babesia, bartonella,
2
and ehrlichia must be ruled out. These tick-borne
2
intracellular pathogens are difficult to diagnose and can establish long-term, persistent infection.
3
–
5
Anaplasma, babesia, and bartonella are underdiagnosed: the nonspecific symptoms of infections with these organisms tend to be ascribed to the more easily identifiable Lyme disease, which often accompanies them.
2
– . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>18216368</pmid><doi>10.1056/NEJMc073063</doi><tpages>4</tpages></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
subjects | Anti-Bacterial Agents - therapeutic use Borrelia burgdorferi Group Chronic Disease Diagnosis, Differential Humans Lyme Disease - diagnosis Tick-Borne Diseases - diagnosis Tick-Borne Diseases - transmission |
title | An Appraisal of “Chronic Lyme Disease” |
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