5HTTLPR Polymorphism and Enlargement of the Pulvinar: Unlocking the Backdoor to the Limbic System

Background The 5HTTLPR genetic variant of the serotonin transporter (SERT), which consists of a long (SERT-l) and short (SERT-s) allele, has emerged as a major factor influencing emotional behavior and brain anatomy. The pulvinar nucleus of the thalamus projects to important limbic nuclei including...

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Veröffentlicht in:	Biological psychiatry (1969) 2007-03, Vol.61 (6), p.813-818
Hauptverfasser:	Young, Keith A, Holcomb, Leigh A, Bonkale, Willy L, Hicks, Paul B, Yazdani, Umar, German, Dwight C
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Bipolar Disorder - genetics Bipolar Disorder - pathology Case-Control Studies Cell Count Depression Depressive Disorder, Major - genetics Depressive Disorder, Major - pathology Female Genetic Variation human Humans Limbic System - cytology Male Matched-Pair Analysis Neurons - cytology Neurons - pathology Organ Size postmortem Psychiatry pulvinar Pulvinar - cytology Reference Values Schizophrenia - genetics Schizophrenia - pathology serotonin Serotonin Plasma Membrane Transport Proteins - genetics thalamus
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