Natural killer cells of Parkinson's disease patients are set up for activation: A possible role for innate immunity in the pathogenesis of this disease

Abstract Neuroinflammation in Parkinson's disease (PD) involves activation of microglia, participation of several inflammatory cytokines, prostaglandins, complement and systemic activation of natural killer (NK) cells, suggesting that innate immunity has a role in the pathogenesis of this disea...

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Veröffentlicht in:	Parkinsonism & related disorders 2008-01, Vol.14 (1), p.46-51
Hauptverfasser:	Mihara, Tomoko, Nakashima, Manabu, Kuroiwa, Ataru, Akitake, Yoshiharu, Ono, Kazuhiko, Hosokawa, Masato, Yamada, Tatsuo, Takahashi, Mitsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Cytokines - metabolism Enzyme-Linked Immunosorbent Assay Female Flow Cytometry Humans Immunity, Innate Innate immunity Killer Cells, Natural - immunology Male Middle Aged Natural killer (NK) Neurology NK Cell Lectin-Like Receptor Subfamily C NKG2A NKG2D Parkinson Disease - immunology Parkinson's disease Receptors, Immunologic - metabolism Receptors, Natural Killer Cell Th1 Cells - immunology Th2 Cells - immunology
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