Treatment of pregnant and non-pregnant rheumatic patients: a survey among Dutch rheumatologists

Summary Background:  The aim of this study was to explore, among Dutch rheumatologists, aspects such as attitude towards guidelines, pharmacotherapy and information needs in the treatment of pregnant as well as non‐pregnant rheumatoid arthritis (RA) patients. Methods:  Fifteen rheumatologists from n...

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Veröffentlicht in:Journal of clinical pharmacy and therapeutics 2008-02, Vol.33 (1), p.39-44
Hauptverfasser: Vroom, F., Van De Laar, M.A.J.F., Van Roon, E.N., Brouwers, J.R.B.J., De Jong-van den Berg, L.T.W.
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container_end_page 44
container_issue 1
container_start_page 39
container_title Journal of clinical pharmacy and therapeutics
container_volume 33
creator Vroom, F.
Van De Laar, M.A.J.F.
Van Roon, E.N.
Brouwers, J.R.B.J.
De Jong-van den Berg, L.T.W.
description Summary Background:  The aim of this study was to explore, among Dutch rheumatologists, aspects such as attitude towards guidelines, pharmacotherapy and information needs in the treatment of pregnant as well as non‐pregnant rheumatoid arthritis (RA) patients. Methods:  Fifteen rheumatologists from nine different hospitals were interviewed by means of a semi‐structured interview. Questions addressing attitude towards guidelines, pharmacotherapy preferences and information needs with respect to the pregnant and non‐pregnant patient were asked. The analysis will be based on descriptive statistics. Results:  Guidelines are used by almost half of the hospitals with respect to pregnant RA patients and by all hospitals for RA patients in general. With respect to pregnant women, nine respondents preferred stopping the medication as soon pregnancy is known. When treating RA patients, in general sulfasalazine and methotrexate would be drugs of first choice. Information is found in international and national books and guidelines. Conclusion:  Dutch rheumatologists are of the view that there is sufficient information on the treatment of RA in pregnant women or women wishing to become pregnant, except for safe use of medication during pregnancy. In the future, pregnancy risk categorization should be updated and discussed regularly. This should be based on more recent literature and experience. A good monitoring system for following all young patients with a rheumatic disease should be set up as a first step to collect more information on the safe use of medication during pregnancy.
doi_str_mv 10.1111/j.1365-2710.2008.00886.x
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Methods:  Fifteen rheumatologists from nine different hospitals were interviewed by means of a semi‐structured interview. Questions addressing attitude towards guidelines, pharmacotherapy preferences and information needs with respect to the pregnant and non‐pregnant patient were asked. The analysis will be based on descriptive statistics. Results:  Guidelines are used by almost half of the hospitals with respect to pregnant RA patients and by all hospitals for RA patients in general. With respect to pregnant women, nine respondents preferred stopping the medication as soon pregnancy is known. When treating RA patients, in general sulfasalazine and methotrexate would be drugs of first choice. Information is found in international and national books and guidelines. Conclusion:  Dutch rheumatologists are of the view that there is sufficient information on the treatment of RA in pregnant women or women wishing to become pregnant, except for safe use of medication during pregnancy. In the future, pregnancy risk categorization should be updated and discussed regularly. This should be based on more recent literature and experience. A good monitoring system for following all young patients with a rheumatic disease should be set up as a first step to collect more information on the safe use of medication during pregnancy.</description><identifier>ISSN: 0269-4727</identifier><identifier>EISSN: 1365-2710</identifier><identifier>DOI: 10.1111/j.1365-2710.2008.00886.x</identifier><identifier>PMID: 18211615</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Antirheumatic Agents - adverse effects ; Antirheumatic Agents - therapeutic use ; Arthritis, Rheumatoid - drug therapy ; Attitude of Health Personnel ; Biological and medical sciences ; Data Collection ; disease modifying anti-rheumatic drugs ; Drug Monitoring - methods ; drug therapy ; Female ; Humans ; Male ; Medical sciences ; Methotrexate - therapeutic use ; Netherlands ; Pharmacology. 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Methods:  Fifteen rheumatologists from nine different hospitals were interviewed by means of a semi‐structured interview. Questions addressing attitude towards guidelines, pharmacotherapy preferences and information needs with respect to the pregnant and non‐pregnant patient were asked. The analysis will be based on descriptive statistics. Results:  Guidelines are used by almost half of the hospitals with respect to pregnant RA patients and by all hospitals for RA patients in general. With respect to pregnant women, nine respondents preferred stopping the medication as soon pregnancy is known. When treating RA patients, in general sulfasalazine and methotrexate would be drugs of first choice. Information is found in international and national books and guidelines. Conclusion:  Dutch rheumatologists are of the view that there is sufficient information on the treatment of RA in pregnant women or women wishing to become pregnant, except for safe use of medication during pregnancy. In the future, pregnancy risk categorization should be updated and discussed regularly. This should be based on more recent literature and experience. A good monitoring system for following all young patients with a rheumatic disease should be set up as a first step to collect more information on the safe use of medication during pregnancy.</description><subject>Antirheumatic Agents - adverse effects</subject><subject>Antirheumatic Agents - therapeutic use</subject><subject>Arthritis, Rheumatoid - drug therapy</subject><subject>Attitude of Health Personnel</subject><subject>Biological and medical sciences</subject><subject>Data Collection</subject><subject>disease modifying anti-rheumatic drugs</subject><subject>Drug Monitoring - methods</subject><subject>drug therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Methotrexate - therapeutic use</subject><subject>Netherlands</subject><subject>Pharmacology. Drug treatments</subject><subject>Practice Guidelines as Topic</subject><subject>Practice Patterns, Physicians' - statistics &amp; numerical data</subject><subject>Pregnancy</subject><subject>Pregnancy Complications - drug therapy</subject><subject>rheumatology</subject><subject>Rheumatology - statistics &amp; numerical data</subject><subject>Sulfasalazine - therapeutic use</subject><subject>survey</subject><issn>0269-4727</issn><issn>1365-2710</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkVtvGjEQha2qVSGkfyHyS_O2xLf1mkp9SEgCrVASUapKebEGrxeW7oXYuwn8-5hyqSXbo_F3juQ5CGFK-jSsq1WfchlHLAkNRojqh61kf_MBdU8PH1GXMDmIRMKSDjrzfkUIkQnjn1GHKkappHEX6Zmz0JS2anCd4bWziwpCDVWKq7qKTg23tG0JTW7wOpwB998wYN-6V7vFUNbVAt-2jVkewbqoF7lv_Dn6lEHh7ZfD3UO_7-9mw3E0eRz9GF5PIiO4lFHMhTSxIUmmjBBMEOAUsvAVRayYp9SY1CoBIFJlMpvGFOaZ4nQQU8MGhA54D13ufdeufmmtb3SZe2OLAipbt14nhHGmYhHAiwPYzkub6rXLS3BbfRxJAL4eAPAGisxBZXJ_4sK4qWRUBu77nnvLC7v970P0LiK90rsk9C6JnUbpfxHpjf45fJqFKuijvT6MyW5OenB_tUx4Eus_DyM9nf4aP0-nN8HsHVxTlHY</recordid><startdate>200802</startdate><enddate>200802</enddate><creator>Vroom, F.</creator><creator>Van De Laar, M.A.J.F.</creator><creator>Van Roon, E.N.</creator><creator>Brouwers, J.R.B.J.</creator><creator>De Jong-van den Berg, L.T.W.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200802</creationdate><title>Treatment of pregnant and non-pregnant rheumatic patients: a survey among Dutch rheumatologists</title><author>Vroom, F. ; Van De Laar, M.A.J.F. ; Van Roon, E.N. ; Brouwers, J.R.B.J. ; De Jong-van den Berg, L.T.W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4366-5346c5c07f8c44240a31af36580e4bd1ccde84aa4d8cfed51abf831951c290193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Antirheumatic Agents - adverse effects</topic><topic>Antirheumatic Agents - therapeutic use</topic><topic>Arthritis, Rheumatoid - drug therapy</topic><topic>Attitude of Health Personnel</topic><topic>Biological and medical sciences</topic><topic>Data Collection</topic><topic>disease modifying anti-rheumatic drugs</topic><topic>Drug Monitoring - methods</topic><topic>drug therapy</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Methotrexate - therapeutic use</topic><topic>Netherlands</topic><topic>Pharmacology. Drug treatments</topic><topic>Practice Guidelines as Topic</topic><topic>Practice Patterns, Physicians' - statistics &amp; numerical data</topic><topic>Pregnancy</topic><topic>Pregnancy Complications - drug therapy</topic><topic>rheumatology</topic><topic>Rheumatology - statistics &amp; numerical data</topic><topic>Sulfasalazine - therapeutic use</topic><topic>survey</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vroom, F.</creatorcontrib><creatorcontrib>Van De Laar, M.A.J.F.</creatorcontrib><creatorcontrib>Van Roon, E.N.</creatorcontrib><creatorcontrib>Brouwers, J.R.B.J.</creatorcontrib><creatorcontrib>De Jong-van den Berg, L.T.W.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical pharmacy and therapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vroom, F.</au><au>Van De Laar, M.A.J.F.</au><au>Van Roon, E.N.</au><au>Brouwers, J.R.B.J.</au><au>De Jong-van den Berg, L.T.W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treatment of pregnant and non-pregnant rheumatic patients: a survey among Dutch rheumatologists</atitle><jtitle>Journal of clinical pharmacy and therapeutics</jtitle><addtitle>J Clin Pharm Ther</addtitle><date>2008-02</date><risdate>2008</risdate><volume>33</volume><issue>1</issue><spage>39</spage><epage>44</epage><pages>39-44</pages><issn>0269-4727</issn><eissn>1365-2710</eissn><abstract>Summary Background:  The aim of this study was to explore, among Dutch rheumatologists, aspects such as attitude towards guidelines, pharmacotherapy and information needs in the treatment of pregnant as well as non‐pregnant rheumatoid arthritis (RA) patients. Methods:  Fifteen rheumatologists from nine different hospitals were interviewed by means of a semi‐structured interview. Questions addressing attitude towards guidelines, pharmacotherapy preferences and information needs with respect to the pregnant and non‐pregnant patient were asked. The analysis will be based on descriptive statistics. Results:  Guidelines are used by almost half of the hospitals with respect to pregnant RA patients and by all hospitals for RA patients in general. With respect to pregnant women, nine respondents preferred stopping the medication as soon pregnancy is known. When treating RA patients, in general sulfasalazine and methotrexate would be drugs of first choice. Information is found in international and national books and guidelines. Conclusion:  Dutch rheumatologists are of the view that there is sufficient information on the treatment of RA in pregnant women or women wishing to become pregnant, except for safe use of medication during pregnancy. 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subjects Antirheumatic Agents - adverse effects
Antirheumatic Agents - therapeutic use
Arthritis, Rheumatoid - drug therapy
Attitude of Health Personnel
Biological and medical sciences
Data Collection
disease modifying anti-rheumatic drugs
Drug Monitoring - methods
drug therapy
Female
Humans
Male
Medical sciences
Methotrexate - therapeutic use
Netherlands
Pharmacology. Drug treatments
Practice Guidelines as Topic
Practice Patterns, Physicians' - statistics & numerical data
Pregnancy
Pregnancy Complications - drug therapy
rheumatology
Rheumatology - statistics & numerical data
Sulfasalazine - therapeutic use
survey
title Treatment of pregnant and non-pregnant rheumatic patients: a survey among Dutch rheumatologists
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