Telomere length assessment: Biomarker of chronic oxidative stress?

Telomeres are nucleoprotein structures, located at the ends of chromosomes and are subject to shortening at each cycle of cell division. They prevent chromosomal ends from being recognized as double strand breaks and protect them from end to end fusion and degradation. Telomeres consist of stretches...

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Veröffentlicht in:	Free radical biology & medicine 2008-02, Vol.44 (3), p.235-246
Hauptverfasser:	Houben, Joyce M.J., Moonen, Harald J.J., van Schooten, Frederik J., Hageman, Geja J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarker Biomarkers - chemistry Biomarkers - metabolism Chronic inflammatory diseases Humans Inflammation - etiology Inflammation - genetics Oxidative Stress Poly(ADP-ribose) Polymerases - metabolism Telomere - chemistry Telomere - genetics Telomere - metabolism Telomere length assesment Telomere-Binding Proteins - metabolism
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