Estrogen-modulated frontal cortical CaMKII activity and behavioral supersensitization induced by prolonged cocaine treatment in female rats

Females have been demonstrated repeatedly to be more sensitive to cocaine. The role of the frontal cortex (FCX) in mediating behavioral sensitization and the underlying signaling pathways are unclear. The study was designed to characterize the role of FCX calcium/calmodulin-dependent protein kinase...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Psychopharmacologia 2007-04, Vol.191 (2), p.323-331
Hauptverfasser:	XUECHU ZHEN, GOSWAMI, Satindra, ABDALI, Syed Amir, FRANKFURT, Maya, FRIEDMAN, Eitan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Biological and medical sciences Brain Calcium-Calmodulin-Dependent Protein Kinase Type 2 Calcium-Calmodulin-Dependent Protein Kinases - drug effects Calcium-Calmodulin-Dependent Protein Kinases - metabolism Cocaine Cocaine - administration & dosage Cocaine - pharmacology Dopamine Uptake Inhibitors - administration & dosage Dopamine Uptake Inhibitors - pharmacology Drug Administration Schedule Estradiol - analogs & derivatives Estradiol - pharmacology Estrogens - pharmacology Female Gender differences Kinases Male Medical sciences Neuropharmacology Ovariectomy Pharmacology Pharmacology. Drug treatments Prefrontal Cortex Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology Psychology. Psychoanalysis. Psychiatry Psychopharmacology Pyramidal Cells Rats Rats, Sprague-Dawley Receptors, Dopamine D1 - drug effects Receptors, Dopamine D1 - metabolism Rodents Sex Factors Signal Transduction - drug effects Substance abuse treatment
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!