Microbicide drug candidates to prevent HIV infection

Summary 25 years after the first HIV/AIDS cases emerged in 1981, the disease continues to spread worldwide, with about 15 000 new infections every day. Although highly active antiretroviral therapy (HAART) has greatly reduced the rate of HIV infection, and the spread of the epidemic, this effect has...

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Veröffentlicht in:	The Lancet (British edition) 2007-03, Vol.369 (9563), p.787-797
Hauptverfasser:	Balzarini, Jan, Prof, Van Damme, Lut, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Adsorption AIDS Anti-HIV Agents - pharmacology Anti-Infective Agents, Local - pharmacology Antiretroviral agents Antiretroviral drugs Atoms & subatomic particles Biological and medical sciences Buffers Cells Clinical trials Clinical Trials, Phase III as Topic - methods Dendritic cells Detergents - pharmacology Developed countries Developing countries Disease prevention Disease transmission Disease Transmission, Infectious - prevention & control Drug development Drug Evaluation, Preclinical - methods Epidemics Feasibility studies Female Gels General aspects Health care policy Highly active antiretroviral therapy HIV HIV - drug effects HIV Infections - prevention & control HIV Infections - transmission HIV Infections - virology Human immunodeficiency virus Human viral diseases Humans Infections Infectious diseases Internal Medicine LDCs Lead compounds Lectins Lymphocytes Male Mathematical models Medical sciences Microbicides Models, Theoretical Pathogens Pharmaceutical industry Population Prevention and actions Proteins Public health. Hygiene Public health. Hygiene-occupational medicine R&D Research & development Sex industry Sexual behavior Sexually transmitted diseases STD Surface-Active Agents - pharmacology Surfactants Treatment Outcome Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Virus Internalization - drug effects Viruses
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