Efficacy of UVA1 phototherapy in 230 patients with various skin diseases
Summary Objective: Investigation of the efficacy of ultraviolet (UV) A1 phototherapy on atopic eczema, scleroderma, granuloma annulare, urticaria pigmentosa, prurigo nodularis, lichen sclerosus et atrophicus, T‐cell lymphoma, keratosis lichenoides chronica, chronic urticaria and some rare, sclerosin...
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| Veröffentlicht in: | Photodermatology, photoimmunology & photomedicine photoimmunology & photomedicine, 2008-02, Vol.24 (1), p.19-23 |
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| container_title | Photodermatology, photoimmunology & photomedicine |
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| creator | Rombold, S. Lobisch, K. Katzer, K. Grazziotin, T. C. Ring, J. Eberlein, B. |
| description | Summary
Objective: Investigation of the efficacy of ultraviolet (UV) A1 phototherapy on atopic eczema, scleroderma, granuloma annulare, urticaria pigmentosa, prurigo nodularis, lichen sclerosus et atrophicus, T‐cell lymphoma, keratosis lichenoides chronica, chronic urticaria and some rare, sclerosing skin diseases.
Methods: The data of 230 patients treated with low‐dose, medium‐dose and high‐dose UVA1 therapy during 6 years were retrospectively analysed. The mean single dose (J/cm2), the mean number of irradiations and the mean total dose (J/cm2) were evaluated. The efficacy of phototherapy was assessed by a grading scale and the number of patients was given in percentage for each group.
Results: Good therapeutic effects of UVA1 therapy were shown in patients with atopic eczema, scleroderma, lichen sclerosus et atrophicus, keratosis lichenoides chronica, prurigo nodularis and with cutaneous T‐cell lymphoma. Positive effects in some patients were seen in the urticaria pigmentosa and granuloma annulare group, no change to slight improvement was seen in most of the patients with rare, sclerosing skin diseases and no effect was seen in the chronic urticaria group.
Conclusion: Besides topical and systemic therapy, UVA1 radiation is a good option of treatment in various skin diseases. It is one of the first‐line treatments for several sclerotic diseases and it often improves pruritus considerably. |
| doi_str_mv | 10.1111/j.1600-0781.2008.00328.x |
| format | Article |
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Objective: Investigation of the efficacy of ultraviolet (UV) A1 phototherapy on atopic eczema, scleroderma, granuloma annulare, urticaria pigmentosa, prurigo nodularis, lichen sclerosus et atrophicus, T‐cell lymphoma, keratosis lichenoides chronica, chronic urticaria and some rare, sclerosing skin diseases.
Methods: The data of 230 patients treated with low‐dose, medium‐dose and high‐dose UVA1 therapy during 6 years were retrospectively analysed. The mean single dose (J/cm2), the mean number of irradiations and the mean total dose (J/cm2) were evaluated. The efficacy of phototherapy was assessed by a grading scale and the number of patients was given in percentage for each group.
Results: Good therapeutic effects of UVA1 therapy were shown in patients with atopic eczema, scleroderma, lichen sclerosus et atrophicus, keratosis lichenoides chronica, prurigo nodularis and with cutaneous T‐cell lymphoma. Positive effects in some patients were seen in the urticaria pigmentosa and granuloma annulare group, no change to slight improvement was seen in most of the patients with rare, sclerosing skin diseases and no effect was seen in the chronic urticaria group.
Conclusion: Besides topical and systemic therapy, UVA1 radiation is a good option of treatment in various skin diseases. It is one of the first‐line treatments for several sclerotic diseases and it often improves pruritus considerably.</description><identifier>ISSN: 0905-4383</identifier><identifier>EISSN: 1600-0781</identifier><identifier>DOI: 10.1111/j.1600-0781.2008.00328.x</identifier><identifier>PMID: 18201353</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adult ; Aged ; Allergic diseases ; atopic eczema ; Biological and medical sciences ; Dermatology ; Female ; Germany - epidemiology ; Humans ; Immunopathology ; Male ; Medical sciences ; Middle Aged ; phototherapy ; Retrospective Studies ; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis ; scleroderma ; Severity of Illness Index ; Skin allergic diseases. Stinging insect allergies ; Skin Diseases - epidemiology ; Skin Diseases - pathology ; Skin Diseases - radiotherapy ; Treatment Outcome ; Ultraviolet Rays ; Ultraviolet Therapy ; UVA1 therapy</subject><ispartof>Photodermatology, photoimmunology & photomedicine, 2008-02, Vol.24 (1), p.19-23</ispartof><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4358-62288d57fb290aefa622633e372798d2308676b5ab05c4b7430b361b717e46d3</citedby><cites>FETCH-LOGICAL-c4358-62288d57fb290aefa622633e372798d2308676b5ab05c4b7430b361b717e46d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1600-0781.2008.00328.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1600-0781.2008.00328.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19998656$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18201353$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rombold, S.</creatorcontrib><creatorcontrib>Lobisch, K.</creatorcontrib><creatorcontrib>Katzer, K.</creatorcontrib><creatorcontrib>Grazziotin, T. C.</creatorcontrib><creatorcontrib>Ring, J.</creatorcontrib><creatorcontrib>Eberlein, B.</creatorcontrib><title>Efficacy of UVA1 phototherapy in 230 patients with various skin diseases</title><title>Photodermatology, photoimmunology & photomedicine</title><addtitle>Photodermatol Photoimmunol Photomed</addtitle><description>Summary
Objective: Investigation of the efficacy of ultraviolet (UV) A1 phototherapy on atopic eczema, scleroderma, granuloma annulare, urticaria pigmentosa, prurigo nodularis, lichen sclerosus et atrophicus, T‐cell lymphoma, keratosis lichenoides chronica, chronic urticaria and some rare, sclerosing skin diseases.
Methods: The data of 230 patients treated with low‐dose, medium‐dose and high‐dose UVA1 therapy during 6 years were retrospectively analysed. The mean single dose (J/cm2), the mean number of irradiations and the mean total dose (J/cm2) were evaluated. The efficacy of phototherapy was assessed by a grading scale and the number of patients was given in percentage for each group.
Results: Good therapeutic effects of UVA1 therapy were shown in patients with atopic eczema, scleroderma, lichen sclerosus et atrophicus, keratosis lichenoides chronica, prurigo nodularis and with cutaneous T‐cell lymphoma. Positive effects in some patients were seen in the urticaria pigmentosa and granuloma annulare group, no change to slight improvement was seen in most of the patients with rare, sclerosing skin diseases and no effect was seen in the chronic urticaria group.
Conclusion: Besides topical and systemic therapy, UVA1 radiation is a good option of treatment in various skin diseases. It is one of the first‐line treatments for several sclerotic diseases and it often improves pruritus considerably.</description><subject>Adult</subject><subject>Aged</subject><subject>Allergic diseases</subject><subject>atopic eczema</subject><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Female</subject><subject>Germany - epidemiology</subject><subject>Humans</subject><subject>Immunopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>phototherapy</subject><subject>Retrospective Studies</subject><subject>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</subject><subject>scleroderma</subject><subject>Severity of Illness Index</subject><subject>Skin allergic diseases. Stinging insect allergies</subject><subject>Skin Diseases - epidemiology</subject><subject>Skin Diseases - pathology</subject><subject>Skin Diseases - radiotherapy</subject><subject>Treatment Outcome</subject><subject>Ultraviolet Rays</subject><subject>Ultraviolet Therapy</subject><subject>UVA1 therapy</subject><issn>0905-4383</issn><issn>1600-0781</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMtu2zAQRYmiRew8fqHgpt1JHZLiQ4suDCONUwSJE-SxJCiJgmnLlkrKif33oWMj3pYbEpxzZgYXIUwgJfH8mqdEACQgFUkpgEoBGFXp5gsafha-oiHkwJOMKTZApyHMASDLgJygAVEUCONsiCaXde1KU25xW-On5xHB3azt235mvem22K0wZYA70zu76gN-c_0Mvxrv2nXAYRHLlQvWBBvO0bfaNMFeHO4z9Pjn8nE8SW7urq7Ho5ukzBhXiaBUqYrLuqA5GFub-CEYs0xSmasqDlNCioKbAniZFTJjUDBBCkmkzUTFztDPfdvOt__WNvR66UJpm8asbNxJS6A0OjKCag-Wvg3B21p33i2N32oCeheinutdVnqXld6FqD9C1Juofj_MWBdLWx3FQ2oR-HEATChNU3uzKl04cnmeK8FF5H7vuTfX2O1_L6Cnk-k0vqKf7H0Xerv59I1faCGZ5Prl9krf_-XkJZcPeszeAej5mZc</recordid><startdate>200802</startdate><enddate>200802</enddate><creator>Rombold, S.</creator><creator>Lobisch, K.</creator><creator>Katzer, K.</creator><creator>Grazziotin, T. C.</creator><creator>Ring, J.</creator><creator>Eberlein, B.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200802</creationdate><title>Efficacy of UVA1 phototherapy in 230 patients with various skin diseases</title><author>Rombold, S. ; Lobisch, K. ; Katzer, K. ; Grazziotin, T. C. ; Ring, J. ; Eberlein, B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4358-62288d57fb290aefa622633e372798d2308676b5ab05c4b7430b361b717e46d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Allergic diseases</topic><topic>atopic eczema</topic><topic>Biological and medical sciences</topic><topic>Dermatology</topic><topic>Female</topic><topic>Germany - epidemiology</topic><topic>Humans</topic><topic>Immunopathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>phototherapy</topic><topic>Retrospective Studies</topic><topic>Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis</topic><topic>scleroderma</topic><topic>Severity of Illness Index</topic><topic>Skin allergic diseases. Stinging insect allergies</topic><topic>Skin Diseases - epidemiology</topic><topic>Skin Diseases - pathology</topic><topic>Skin Diseases - radiotherapy</topic><topic>Treatment Outcome</topic><topic>Ultraviolet Rays</topic><topic>Ultraviolet Therapy</topic><topic>UVA1 therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rombold, S.</creatorcontrib><creatorcontrib>Lobisch, K.</creatorcontrib><creatorcontrib>Katzer, K.</creatorcontrib><creatorcontrib>Grazziotin, T. C.</creatorcontrib><creatorcontrib>Ring, J.</creatorcontrib><creatorcontrib>Eberlein, B.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Photodermatology, photoimmunology & photomedicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rombold, S.</au><au>Lobisch, K.</au><au>Katzer, K.</au><au>Grazziotin, T. C.</au><au>Ring, J.</au><au>Eberlein, B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy of UVA1 phototherapy in 230 patients with various skin diseases</atitle><jtitle>Photodermatology, photoimmunology & photomedicine</jtitle><addtitle>Photodermatol Photoimmunol Photomed</addtitle><date>2008-02</date><risdate>2008</risdate><volume>24</volume><issue>1</issue><spage>19</spage><epage>23</epage><pages>19-23</pages><issn>0905-4383</issn><eissn>1600-0781</eissn><abstract>Summary
Objective: Investigation of the efficacy of ultraviolet (UV) A1 phototherapy on atopic eczema, scleroderma, granuloma annulare, urticaria pigmentosa, prurigo nodularis, lichen sclerosus et atrophicus, T‐cell lymphoma, keratosis lichenoides chronica, chronic urticaria and some rare, sclerosing skin diseases.
Methods: The data of 230 patients treated with low‐dose, medium‐dose and high‐dose UVA1 therapy during 6 years were retrospectively analysed. The mean single dose (J/cm2), the mean number of irradiations and the mean total dose (J/cm2) were evaluated. The efficacy of phototherapy was assessed by a grading scale and the number of patients was given in percentage for each group.
Results: Good therapeutic effects of UVA1 therapy were shown in patients with atopic eczema, scleroderma, lichen sclerosus et atrophicus, keratosis lichenoides chronica, prurigo nodularis and with cutaneous T‐cell lymphoma. Positive effects in some patients were seen in the urticaria pigmentosa and granuloma annulare group, no change to slight improvement was seen in most of the patients with rare, sclerosing skin diseases and no effect was seen in the chronic urticaria group.
Conclusion: Besides topical and systemic therapy, UVA1 radiation is a good option of treatment in various skin diseases. It is one of the first‐line treatments for several sclerotic diseases and it often improves pruritus considerably.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>18201353</pmid><doi>10.1111/j.1600-0781.2008.00328.x</doi><tpages>5</tpages></addata></record> |
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| ispartof | Photodermatology, photoimmunology & photomedicine, 2008-02, Vol.24 (1), p.19-23 |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Aged Allergic diseases atopic eczema Biological and medical sciences Dermatology Female Germany - epidemiology Humans Immunopathology Male Medical sciences Middle Aged phototherapy Retrospective Studies Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis scleroderma Severity of Illness Index Skin allergic diseases. Stinging insect allergies Skin Diseases - epidemiology Skin Diseases - pathology Skin Diseases - radiotherapy Treatment Outcome Ultraviolet Rays Ultraviolet Therapy UVA1 therapy |
| title | Efficacy of UVA1 phototherapy in 230 patients with various skin diseases |
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