E-cadherin expression and epidermal growth factor receptor mutation status predict outcome in non-small cell lung cancer patients treated with gefitinib

It is known that an epidermal growth factor receptor (EGFR) gene mutation(s) is present in a percentage of non-small cell lung cancers (NSCLCs). Gefitinib, an inhibitor of the tyrosine kinase activity of EGFR, is effective on most of them. The EGFR mutation status alone cannot fully predict the resp...

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Veröffentlicht in:Oncology reports 2008-02, Vol.19 (2), p.377-383
Hauptverfasser: MIYANAGA, Akihiko, GEMMA, Akihiko, TANAKA, Tomoaki, YOSHIMURA, Akinobu, KOBAYASHI, Kunihiko, IWANAMI, Hiroshi, HAGIWARA, Koichi, TSUBOI, Eitaka, KUDOH, Shoji, ANDO, Masahiro, KOSAIHIRA, Seiji, NORO, Rintaro, MINEGISHI, Yuji, KATAOKA, Kiyoko, NARA, Michiya, OKANO, Tetsuya, MIYAZAWA, Hitoshi
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Sprache:eng
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