Towards a muscarinic hypothesis of schizophrenia

Although the neurotransmitter dopamine plays a prominent role in the pathogenesis and treatment of schizophrenia, the dopamine hypothesis of schizophrenia fails to explain all aspects of this disorder. It is increasingly evident that the pathology of schizophrenia also involves other neurotransmitte...

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Veröffentlicht in:	Molecular psychiatry 2007-03, Vol.12 (3), p.232-246
Hauptverfasser:	Raedler, T J, Bymaster, F P, Tandon, R, Copolov, D, Dean, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine receptors (muscarinic) Adult and adolescent clinical studies Amphetamines Animals Autopsy Behavioral Sciences Biological and medical sciences Biological Psychology Cholinergic transmission Dopamine Dopamine - metabolism Enzymes feature-review Humans Hypotheses Medical imaging Medical sciences Medicine Medicine & Public Health Memory Mental disorders Mental health Nervous system Neuroimaging Neurons Neurosciences Pathogenesis Pathology Pathophysiology Pharmacotherapy Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Receptors, Muscarinic - genetics Receptors, Muscarinic - physiology Schizophrenia Schizophrenia - genetics Schizophrenia - metabolism Schizophrenia - pathology Tomography
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