Integrated Portable Polymerase Chain Reaction-Capillary Electrophoresis Microsystem for Rapid Forensic Short Tandem Repeat Typing

A portable forensic genetic analysis system consisting of a microfluidic device for amplification and separation of short tandem repeat (STR) fragments as well as an instrument for chip operation and four-color fluorescence detection has been developed. The microdevice performs polymerase chain reac...

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Veröffentlicht in:	Analytical chemistry (Washington) 2007-03, Vol.79 (5), p.1881-1889
Hauptverfasser:	Liu, Peng, Seo, Tae Seok, Beyor, Nathaniel, Shin, Kyoung-Jin, Scherer, James R, Mathies, Richard A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Chemistry Chromatographic methods and physical methods associated with chromatography Chromosomes, Human, Y - genetics DNA Fingerprinting - instrumentation Electrophoresis, Capillary - instrumentation Exact sciences and technology Female Fluorescence Forensic chemistry Forensic Genetics - instrumentation Gene amplification Gene loci General, instrumentation Genetics Humans Male Microfluidic Analytical Techniques - instrumentation Microsatellite Repeats - genetics Other chromatographic methods Polymerase Chain Reaction - instrumentation Semiconductors Sex Ratio
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