Multiple gastrointestinal stromal tumors in neurofibromatosis type 1 treated with laparoscopic surgery
Gastrointestinal stromal tumors (GISTs) have been reported to occasionally occur in patients with neurofibromatosis type 1 (NF-1), and many cases have had multiple lesions predominantly involving the small intestine. We report herein a case of multiple GISTs associated with NF-1 from whom laparoscop...
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| Veröffentlicht in: | Acta medica Okayama 2007-02, Vol.61 (1), p.47-50 |
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| creator | Tsukuda, Kazunori Ikeda, Eiji Takagi, Shoji Miyake, Takayoshi Muraoka, Takayuki Watanabe, Keitaro Hirai, Ryuji Moriyama, Shigeharu Nawa, Sugato Kunitomo, Tadayoshi Tsuji, Hisashi |
| description | Gastrointestinal stromal tumors (GISTs) have been reported to occasionally occur in patients with neurofibromatosis type 1 (NF-1), and many cases have had multiple lesions predominantly involving the small intestine. We report herein a case of multiple GISTs associated with NF-1 from whom laparoscopic surgery was beneficial. In a 79-year-old female admitted with anemia and melena, the abdominal computed tomography revealed a tumor arising from the small intestine. Laparoscopic surgery was performed, and another small tumor was revealed during laparoscopic observation. Extracorporeal partial and wedge resection of the small intestine were undertaken. Both lesions were diagnosed as typical GISTs of low risk. Laparoscopic surgery would be useful for examination and a minimally invasive approach to tumors of the small intestine, especially on cases with the possibility of multiple tumors. |
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We report herein a case of multiple GISTs associated with NF-1 from whom laparoscopic surgery was beneficial. In a 79-year-old female admitted with anemia and melena, the abdominal computed tomography revealed a tumor arising from the small intestine. Laparoscopic surgery was performed, and another small tumor was revealed during laparoscopic observation. Extracorporeal partial and wedge resection of the small intestine were undertaken. Both lesions were diagnosed as typical GISTs of low risk. Laparoscopic surgery would be useful for examination and a minimally invasive approach to tumors of the small intestine, especially on cases with the possibility of multiple tumors.</description><subject>Aged</subject><subject>Digestive System Surgical Procedures - methods</subject><subject>Female</subject><subject>Gastrointestinal Stromal Tumors - complications</subject><subject>Gastrointestinal Stromal Tumors - diagnosis</subject><subject>Gastrointestinal Stromal Tumors - surgery</subject><subject>Humans</subject><subject>Ileal Neoplasms - complications</subject><subject>Ileal Neoplasms - diagnosis</subject><subject>Ileal Neoplasms - surgery</subject><subject>Incidental Findings</subject><subject>Laparoscopy</subject><subject>Neurofibromatosis 1 - complications</subject><subject>Radiography, Abdominal</subject><subject>Tomography, X-Ray Computed</subject><subject>Treatment Outcome</subject><issn>0386-300X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kE1LAzEQhnNQbK3-BcnJ28Lko032KMUvqHhR8LZks7M1JbtZ84H037tincvDvDwMzHtGliD0phIAHwtymdIBgMt6AxdkwZQQXEu-JP1L8dlNHunepByDGzOm7Ebj6e86zMxlCDFRN9IRSwy9a3_zHJJLNB8npIzmiCZjR79d_qTeTCaGZMPkLE0l7jEer8h5b3zC6xNX5P3h_m37VO1eH5-3d7vqwIXIla57xjorocW1sTgP7-pO1i0oqbTQArTEXqvWIFeGdWuQumbAgAtrgXOxIrd_d6cYvsr8STO4ZNF7M2IoqVGzBKpez-LNSSztgF0zRTeYeGz-mxE_28JhUA</recordid><startdate>200702</startdate><enddate>200702</enddate><creator>Tsukuda, Kazunori</creator><creator>Ikeda, Eiji</creator><creator>Takagi, Shoji</creator><creator>Miyake, Takayoshi</creator><creator>Muraoka, Takayuki</creator><creator>Watanabe, Keitaro</creator><creator>Hirai, Ryuji</creator><creator>Moriyama, Shigeharu</creator><creator>Nawa, Sugato</creator><creator>Kunitomo, Tadayoshi</creator><creator>Tsuji, Hisashi</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200702</creationdate><title>Multiple gastrointestinal stromal tumors in neurofibromatosis type 1 treated with laparoscopic surgery</title><author>Tsukuda, Kazunori ; 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We report herein a case of multiple GISTs associated with NF-1 from whom laparoscopic surgery was beneficial. In a 79-year-old female admitted with anemia and melena, the abdominal computed tomography revealed a tumor arising from the small intestine. Laparoscopic surgery was performed, and another small tumor was revealed during laparoscopic observation. Extracorporeal partial and wedge resection of the small intestine were undertaken. Both lesions were diagnosed as typical GISTs of low risk. Laparoscopic surgery would be useful for examination and a minimally invasive approach to tumors of the small intestine, especially on cases with the possibility of multiple tumors.</abstract><cop>Japan</cop><pmid>17332842</pmid><tpages>4</tpages></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Open Access Titles of Japan; Alma/SFX Local Collection |
| subjects | Aged Digestive System Surgical Procedures - methods Female Gastrointestinal Stromal Tumors - complications Gastrointestinal Stromal Tumors - diagnosis Gastrointestinal Stromal Tumors - surgery Humans Ileal Neoplasms - complications Ileal Neoplasms - diagnosis Ileal Neoplasms - surgery Incidental Findings Laparoscopy Neurofibromatosis 1 - complications Radiography, Abdominal Tomography, X-Ray Computed Treatment Outcome |
| title | Multiple gastrointestinal stromal tumors in neurofibromatosis type 1 treated with laparoscopic surgery |
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