Effect of spermine on lipid profile and HDL functionality in the streptozotocin-induced diabetic rat model

This study aimed to investigate the effect of spermine (Spm) as a chemical chaperone and glycation inhibitor on the lipid profile and HDL functionality in the short- and long-term treatment of the STZ-induced diabetic rats. Male Wistar rats were divided into 4 groups (control, n = 7; diabetic, n = 9...

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Veröffentlicht in:	Life sciences (1973) 2008-01, Vol.82 (5), p.301-307
Hauptverfasser:	Jafarnejad, A., Bathaie, S.Z., Nakhjavani, M., Hassan, M.Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Aryldialkylphosphatase - blood Blood Glucose - analysis Cholesterol acyltransferase Diabetes complication Diabetes mellitus Diabetes Mellitus, Experimental - blood Diabetes Mellitus, Experimental - drug therapy Glycation End Products, Advanced - blood HDL functionality Hypolipidemic Agents - therapeutic use Insulin - blood Lecithin Lipid Metabolism Lipid profile Lipoproteins, HDL - blood Male Paraoxonase 1 Phosphatidylcholine-Sterol O-Acyltransferase - blood Rats Rats, Wistar Spermine Spermine - therapeutic use
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