The metabolic syndrome and the carotid artery structure in noninstitutionalized elderly subjects the three-city Study
In contrast to the young adult population, limited data are presently available regarding the epidemiology of the metabolic syndrome (MetS) and its relationship with cardiovascular disease risk in the elderly. We have investigated the frequency of the MetS and its association with the carotid artery...
Gespeichert in:
| Veröffentlicht in: | Stroke (1970) 2007-03, Vol.38 (3), p.893-899 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 899 |
|---|---|
| container_issue | 3 |
| container_start_page | 893 |
| container_title | Stroke (1970) |
| container_volume | 38 |
| creator | EMPANA, Jean-Philippe ZUREIK, Mahmoud GARIEPY, Jerome COURBON, Dominique DARTIGUES, Jean Francois RITCHIE, Karen TZOURIO, Christophe ALPEROVITCH, Annick DUCIMETIERE, Pierre |
| description | In contrast to the young adult population, limited data are presently available regarding the epidemiology of the metabolic syndrome (MetS) and its relationship with cardiovascular disease risk in the elderly. We have investigated the frequency of the MetS and its association with the carotid artery structure in an elderly free-living population.
The study population consists of 5585 French noninstitutionalized elderly men and women aged 65 to 85 years, free of diabetes, who participated in the multicenter Three City Study and who underwent ultrasound examination of the carotid arteries at baseline examination between March 1999 and March 2001. The MetS was defined according to the National Cholesterol Education Program Adult Treatment Panel III criteria.
The MetS was present in 12.1% of the study participants, with slightly higher rates in men. Subjects with the MetS had higher frequency of carotid plaques (odds ratio, 1.30; 95% CI, 1.09 to 1.55), higher intima-media thickness of the common carotid artery (odds ratio, 1.81; 95% CI, 1.37 to 2.41), and higher lumen diameter (odds ratio, 2.17; 95% CI, 1.61 to 2.94) (upper quintiles) after adjustment for other cardiovascular risk factors. This association was observed in both genders and in subjects without prevalent cardiovascular disease. Elevated blood pressure as defined in the MetS was the main determinant of the relations between the MetS and the carotid parameters, especially the lumen diameter.
The present data suggest that noninstitutionalized elderly subjects with the MetS have altered structure of the carotid arteries. |
| doi_str_mv | 10.1161/01.STR.0000257983.62530.75 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_70213570</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>70213570</sourcerecordid><originalsourceid>FETCH-LOGICAL-c325t-6cc5234caaf02fa5a24b9dd868973316f469cc3a7125ff1351ae3e3536e6fca3</originalsourceid><addsrcrecordid>eNpFkE1r3DAQhkVoabZp_0IQheZmVx-WbPdWQtMEAoVm72JWGhMFW071cXB_fZVkYWcOc5jnnYGHkC-ctZxr_o3x9mH_p2W1hOrHQbZaKMnaXp2RHVeiazothndkx5gcG9GN4zn5mNLTCy8H9YGc817UVsOOlP0j0gUzHNbZW5q24OK6IIXgaK4rC3HN3lGIGeNGU47F5hKR-kDDGnxI2eeS_Rpg9v_QUZwdxrmS5fCENqfXK_kxIjbW540-5OK2T-T9BHPCz8d5QfY3P_fXt83971931z_uGyuFyo22VgnZWYCJiQkUiO4wOjfoYeyl5Hrq9GithJ4LNU1cKg4oUSqpUU8W5AW5ejv7HNe_BVM2i08W5xkCriWZnoka6lkFv7-BNq4pRZzMc_QLxM1wZl6cG8ZNdW5Ozs2rc9OrGr48fimHBd0pepRcga9HAJKFeYoQrE8nblADHzsp_wMqtI20</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>70213570</pqid></control><display><type>article</type><title>The metabolic syndrome and the carotid artery structure in noninstitutionalized elderly subjects the three-city Study</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><source>EZB Electronic Journals Library</source><source>American Heart Association</source><source>Journals@Ovid Complete</source><creator>EMPANA, Jean-Philippe ; ZUREIK, Mahmoud ; GARIEPY, Jerome ; COURBON, Dominique ; DARTIGUES, Jean Francois ; RITCHIE, Karen ; TZOURIO, Christophe ; ALPEROVITCH, Annick ; DUCIMETIERE, Pierre</creator><creatorcontrib>EMPANA, Jean-Philippe ; ZUREIK, Mahmoud ; GARIEPY, Jerome ; COURBON, Dominique ; DARTIGUES, Jean Francois ; RITCHIE, Karen ; TZOURIO, Christophe ; ALPEROVITCH, Annick ; DUCIMETIERE, Pierre</creatorcontrib><description>In contrast to the young adult population, limited data are presently available regarding the epidemiology of the metabolic syndrome (MetS) and its relationship with cardiovascular disease risk in the elderly. We have investigated the frequency of the MetS and its association with the carotid artery structure in an elderly free-living population.
The study population consists of 5585 French noninstitutionalized elderly men and women aged 65 to 85 years, free of diabetes, who participated in the multicenter Three City Study and who underwent ultrasound examination of the carotid arteries at baseline examination between March 1999 and March 2001. The MetS was defined according to the National Cholesterol Education Program Adult Treatment Panel III criteria.
The MetS was present in 12.1% of the study participants, with slightly higher rates in men. Subjects with the MetS had higher frequency of carotid plaques (odds ratio, 1.30; 95% CI, 1.09 to 1.55), higher intima-media thickness of the common carotid artery (odds ratio, 1.81; 95% CI, 1.37 to 2.41), and higher lumen diameter (odds ratio, 2.17; 95% CI, 1.61 to 2.94) (upper quintiles) after adjustment for other cardiovascular risk factors. This association was observed in both genders and in subjects without prevalent cardiovascular disease. Elevated blood pressure as defined in the MetS was the main determinant of the relations between the MetS and the carotid parameters, especially the lumen diameter.
The present data suggest that noninstitutionalized elderly subjects with the MetS have altered structure of the carotid arteries.</description><identifier>ISSN: 0039-2499</identifier><identifier>EISSN: 1524-4628</identifier><identifier>DOI: 10.1161/01.STR.0000257983.62530.75</identifier><identifier>PMID: 17272758</identifier><identifier>CODEN: SJCCA7</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Aged ; Aged, 80 and over ; Atherosclerosis (general aspects, experimental research) ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Carotid Arteries - diagnostic imaging ; Carotid Artery Diseases - diagnostic imaging ; Carotid Artery Diseases - epidemiology ; Female ; France - epidemiology ; Humans ; Male ; Medical sciences ; Metabolic Syndrome - diagnostic imaging ; Metabolic Syndrome - epidemiology ; Neurology ; Neurosurgery ; Prospective Studies ; Skull, brain, vascular surgery ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Ultrasonography ; Vascular diseases and vascular malformations of the nervous system</subject><ispartof>Stroke (1970), 2007-03, Vol.38 (3), p.893-899</ispartof><rights>2007 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c325t-6cc5234caaf02fa5a24b9dd868973316f469cc3a7125ff1351ae3e3536e6fca3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,3673,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18581943$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17272758$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>EMPANA, Jean-Philippe</creatorcontrib><creatorcontrib>ZUREIK, Mahmoud</creatorcontrib><creatorcontrib>GARIEPY, Jerome</creatorcontrib><creatorcontrib>COURBON, Dominique</creatorcontrib><creatorcontrib>DARTIGUES, Jean Francois</creatorcontrib><creatorcontrib>RITCHIE, Karen</creatorcontrib><creatorcontrib>TZOURIO, Christophe</creatorcontrib><creatorcontrib>ALPEROVITCH, Annick</creatorcontrib><creatorcontrib>DUCIMETIERE, Pierre</creatorcontrib><title>The metabolic syndrome and the carotid artery structure in noninstitutionalized elderly subjects the three-city Study</title><title>Stroke (1970)</title><addtitle>Stroke</addtitle><description>In contrast to the young adult population, limited data are presently available regarding the epidemiology of the metabolic syndrome (MetS) and its relationship with cardiovascular disease risk in the elderly. We have investigated the frequency of the MetS and its association with the carotid artery structure in an elderly free-living population.
The study population consists of 5585 French noninstitutionalized elderly men and women aged 65 to 85 years, free of diabetes, who participated in the multicenter Three City Study and who underwent ultrasound examination of the carotid arteries at baseline examination between March 1999 and March 2001. The MetS was defined according to the National Cholesterol Education Program Adult Treatment Panel III criteria.
The MetS was present in 12.1% of the study participants, with slightly higher rates in men. Subjects with the MetS had higher frequency of carotid plaques (odds ratio, 1.30; 95% CI, 1.09 to 1.55), higher intima-media thickness of the common carotid artery (odds ratio, 1.81; 95% CI, 1.37 to 2.41), and higher lumen diameter (odds ratio, 2.17; 95% CI, 1.61 to 2.94) (upper quintiles) after adjustment for other cardiovascular risk factors. This association was observed in both genders and in subjects without prevalent cardiovascular disease. Elevated blood pressure as defined in the MetS was the main determinant of the relations between the MetS and the carotid parameters, especially the lumen diameter.
The present data suggest that noninstitutionalized elderly subjects with the MetS have altered structure of the carotid arteries.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Atherosclerosis (general aspects, experimental research)</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology. Vascular system</subject><subject>Carotid Arteries - diagnostic imaging</subject><subject>Carotid Artery Diseases - diagnostic imaging</subject><subject>Carotid Artery Diseases - epidemiology</subject><subject>Female</subject><subject>France - epidemiology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Metabolic Syndrome - diagnostic imaging</subject><subject>Metabolic Syndrome - epidemiology</subject><subject>Neurology</subject><subject>Neurosurgery</subject><subject>Prospective Studies</subject><subject>Skull, brain, vascular surgery</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Ultrasonography</subject><subject>Vascular diseases and vascular malformations of the nervous system</subject><issn>0039-2499</issn><issn>1524-4628</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1r3DAQhkVoabZp_0IQheZmVx-WbPdWQtMEAoVm72JWGhMFW071cXB_fZVkYWcOc5jnnYGHkC-ctZxr_o3x9mH_p2W1hOrHQbZaKMnaXp2RHVeiazothndkx5gcG9GN4zn5mNLTCy8H9YGc817UVsOOlP0j0gUzHNbZW5q24OK6IIXgaK4rC3HN3lGIGeNGU47F5hKR-kDDGnxI2eeS_Rpg9v_QUZwdxrmS5fCENqfXK_kxIjbW540-5OK2T-T9BHPCz8d5QfY3P_fXt83971931z_uGyuFyo22VgnZWYCJiQkUiO4wOjfoYeyl5Hrq9GithJ4LNU1cKg4oUSqpUU8W5AW5ejv7HNe_BVM2i08W5xkCriWZnoka6lkFv7-BNq4pRZzMc_QLxM1wZl6cG8ZNdW5Ozs2rc9OrGr48fimHBd0pepRcga9HAJKFeYoQrE8nblADHzsp_wMqtI20</recordid><startdate>20070301</startdate><enddate>20070301</enddate><creator>EMPANA, Jean-Philippe</creator><creator>ZUREIK, Mahmoud</creator><creator>GARIEPY, Jerome</creator><creator>COURBON, Dominique</creator><creator>DARTIGUES, Jean Francois</creator><creator>RITCHIE, Karen</creator><creator>TZOURIO, Christophe</creator><creator>ALPEROVITCH, Annick</creator><creator>DUCIMETIERE, Pierre</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070301</creationdate><title>The metabolic syndrome and the carotid artery structure in noninstitutionalized elderly subjects the three-city Study</title><author>EMPANA, Jean-Philippe ; ZUREIK, Mahmoud ; GARIEPY, Jerome ; COURBON, Dominique ; DARTIGUES, Jean Francois ; RITCHIE, Karen ; TZOURIO, Christophe ; ALPEROVITCH, Annick ; DUCIMETIERE, Pierre</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c325t-6cc5234caaf02fa5a24b9dd868973316f469cc3a7125ff1351ae3e3536e6fca3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Atherosclerosis (general aspects, experimental research)</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Cardiology. Vascular system</topic><topic>Carotid Arteries - diagnostic imaging</topic><topic>Carotid Artery Diseases - diagnostic imaging</topic><topic>Carotid Artery Diseases - epidemiology</topic><topic>Female</topic><topic>France - epidemiology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Metabolic Syndrome - diagnostic imaging</topic><topic>Metabolic Syndrome - epidemiology</topic><topic>Neurology</topic><topic>Neurosurgery</topic><topic>Prospective Studies</topic><topic>Skull, brain, vascular surgery</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Ultrasonography</topic><topic>Vascular diseases and vascular malformations of the nervous system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>EMPANA, Jean-Philippe</creatorcontrib><creatorcontrib>ZUREIK, Mahmoud</creatorcontrib><creatorcontrib>GARIEPY, Jerome</creatorcontrib><creatorcontrib>COURBON, Dominique</creatorcontrib><creatorcontrib>DARTIGUES, Jean Francois</creatorcontrib><creatorcontrib>RITCHIE, Karen</creatorcontrib><creatorcontrib>TZOURIO, Christophe</creatorcontrib><creatorcontrib>ALPEROVITCH, Annick</creatorcontrib><creatorcontrib>DUCIMETIERE, Pierre</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Stroke (1970)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>EMPANA, Jean-Philippe</au><au>ZUREIK, Mahmoud</au><au>GARIEPY, Jerome</au><au>COURBON, Dominique</au><au>DARTIGUES, Jean Francois</au><au>RITCHIE, Karen</au><au>TZOURIO, Christophe</au><au>ALPEROVITCH, Annick</au><au>DUCIMETIERE, Pierre</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The metabolic syndrome and the carotid artery structure in noninstitutionalized elderly subjects the three-city Study</atitle><jtitle>Stroke (1970)</jtitle><addtitle>Stroke</addtitle><date>2007-03-01</date><risdate>2007</risdate><volume>38</volume><issue>3</issue><spage>893</spage><epage>899</epage><pages>893-899</pages><issn>0039-2499</issn><eissn>1524-4628</eissn><coden>SJCCA7</coden><abstract>In contrast to the young adult population, limited data are presently available regarding the epidemiology of the metabolic syndrome (MetS) and its relationship with cardiovascular disease risk in the elderly. We have investigated the frequency of the MetS and its association with the carotid artery structure in an elderly free-living population.
The study population consists of 5585 French noninstitutionalized elderly men and women aged 65 to 85 years, free of diabetes, who participated in the multicenter Three City Study and who underwent ultrasound examination of the carotid arteries at baseline examination between March 1999 and March 2001. The MetS was defined according to the National Cholesterol Education Program Adult Treatment Panel III criteria.
The MetS was present in 12.1% of the study participants, with slightly higher rates in men. Subjects with the MetS had higher frequency of carotid plaques (odds ratio, 1.30; 95% CI, 1.09 to 1.55), higher intima-media thickness of the common carotid artery (odds ratio, 1.81; 95% CI, 1.37 to 2.41), and higher lumen diameter (odds ratio, 2.17; 95% CI, 1.61 to 2.94) (upper quintiles) after adjustment for other cardiovascular risk factors. This association was observed in both genders and in subjects without prevalent cardiovascular disease. Elevated blood pressure as defined in the MetS was the main determinant of the relations between the MetS and the carotid parameters, especially the lumen diameter.
The present data suggest that noninstitutionalized elderly subjects with the MetS have altered structure of the carotid arteries.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>17272758</pmid><doi>10.1161/01.STR.0000257983.62530.75</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0039-2499 |
| ispartof | Stroke (1970), 2007-03, Vol.38 (3), p.893-899 |
| issn | 0039-2499 1524-4628 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70213570 |
| source | MEDLINE; Alma/SFX Local Collection; EZB Electronic Journals Library; American Heart Association; Journals@Ovid Complete |
| subjects | Aged Aged, 80 and over Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Carotid Arteries - diagnostic imaging Carotid Artery Diseases - diagnostic imaging Carotid Artery Diseases - epidemiology Female France - epidemiology Humans Male Medical sciences Metabolic Syndrome - diagnostic imaging Metabolic Syndrome - epidemiology Neurology Neurosurgery Prospective Studies Skull, brain, vascular surgery Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Ultrasonography Vascular diseases and vascular malformations of the nervous system |
| title | The metabolic syndrome and the carotid artery structure in noninstitutionalized elderly subjects the three-city Study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T17%3A24%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20metabolic%20syndrome%20and%20the%20carotid%20artery%20structure%20in%20noninstitutionalized%20elderly%20subjects%20the%20three-city%20Study&rft.jtitle=Stroke%20(1970)&rft.au=EMPANA,%20Jean-Philippe&rft.date=2007-03-01&rft.volume=38&rft.issue=3&rft.spage=893&rft.epage=899&rft.pages=893-899&rft.issn=0039-2499&rft.eissn=1524-4628&rft.coden=SJCCA7&rft_id=info:doi/10.1161/01.STR.0000257983.62530.75&rft_dat=%3Cproquest_cross%3E70213570%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=70213570&rft_id=info:pmid/17272758&rfr_iscdi=true |