Preventative ibandronate treatment has the most beneficial effect on the microstructure of bone in experimental tumor osteolysis

We investigated the effect of ibandronate on three-dimensional (3-D) microstructure and bone mass in experimentally induced tumor osteolysis. Walker carcinosarcoma cells were implanted into the left femur of female rats that received 26-day ibandronate pretreatment followed by continued therapy or i...

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Veröffentlicht in:	Journal of bone and mineral metabolism 2007-03, Vol.25 (2), p.86-92
Hauptverfasser:	KURTH, Andreas A, KIM, Soo-Zin, SHEA, Marie, BAUSS, Frieder, HAYES, Wilson C, MÜLLER, Ralph
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bone and Bones - drug effects Bone and Bones - pathology Bone and Bones - ultrastructure Bone Density Conservation Agents - therapeutic use Bones Bones, joints and connective tissue. Antiinflammatory agents Carcinoma 256, Walker - drug therapy Carcinoma 256, Walker - pathology Diphosphonates - therapeutic use Disease Models, Animal Diseases of the osteoarticular system Female Femur - drug effects Femur - pathology Image Processing, Computer-Assisted Medical sciences Microstructure Osteoporosis Pharmacology. Drug treatments Rats Rodents Tumors of striated muscle and skeleton
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