Increased expression of hypothalamic leptin receptor and adiponectin accompany resistance to dietary-induced obesity and infertility in female C57BL 6J mice

Background: Obesity is strongly associated with female infertility, but the mechanisms underlying this relationship are largely unknown. Methods: We investigated the effect of increasing dietary fat percentage upon body mass, hypothalamic neuropeptide gene expression, adipose hormone secretion and f...

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Veröffentlicht in:	International Journal of Obesity 2007-03, Vol.31 (3), p.395-402
Hauptverfasser:	Tortoriello, D V, McMinn, J E, Chua, S C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes Adiponectin - blood Adipose tissue Agouti-Related Protein Animals Biological and medical sciences Body fat Body Weight Complications and side effects Diagnosis Dietary Fats - administration & dosage Diseases of the digestive system Epidemiology Feeding. Feeding behavior Female Females Fertility Fundamental and applied biological sciences. Psychology Genetic aspects Genotype & phenotype Genotypes Gonadotropin-Releasing Hormone - analysis Health aspects Health Promotion and Disease Prevention Hypothalamus - chemistry Infertility Infertility, Female Infertility, Female - metabolism Inflammation Insulin - metabolism Intercellular Signaling Peptides and Proteins - analysis Internal Medicine Medical sciences Medicine Medicine & Public Health Metabolic Diseases Mice Mice, Inbred C57BL Mice, Inbred DBA Mutation Neuropeptide Y - analysis Neuropeptides Neurotransmitter receptors Obesity Obesity - metabolism original-article Pregnancy Pro-Opiomelanocortin - analysis Public Health Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Receptors, Cell Surface - analysis Receptors, Leptin Resistin - analysis Risk factors Tissue Plasminogen Activator - blood Vertebrates: anatomy and physiology, studies on body, several organs or systems
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