Zidovudine and interferon-α treatment induces a high response rate and reduces HTLV-1 proviral load and VEGF plasma levels in patients with adult T-cell leukemia from North East Iran

Human T-cell lymphotropic virus type I (HTLV-I) associated adult T-cell leukemia lymphoma (ATLL) is endemic in southern Japan, the Caribbean, intertropical Africa, and Brazil. Recently north east Iran, particularly the region of Mashhad, has been recognized as a new endemic region. ATLL is an aggres...

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Veröffentlicht in:	Leukemia & lymphoma 2007-02, Vol.48 (2), p.330-336
Hauptverfasser:	Kchour, Ghada, Makhoul, Nadine J., Mahmoudi, Mahmoud, Kooshyar, Mohamad-Mehdi, Shirdel, Abbas, Rastin, Maryam, Rafatpanah, Houshang, Tarhini, Mahdi, Zalloua, Pierre A., Hermine, Olivier, Farid, Reza, Bazarbachi, Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiviral Agents - therapeutic use ATLL Drug Therapy, Combination Female HTLV-I HTLV-I Infections - drug therapy HTLV-I Infections - virology Human T-lymphotropic virus 1 - drug effects Humans interferon Interferon-alpha - therapeutic use Iran - epidemiology Leukemia-Lymphoma, Adult T-Cell - blood Leukemia-Lymphoma, Adult T-Cell - drug therapy Leukemia-Lymphoma, Adult T-Cell - virology Male Middle Aged Proviruses - isolation & purification Treatment Outcome Vascular Endothelial Growth Factor A - blood Viral Load zidovudine Zidovudine - therapeutic use
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