Polymorphism of FecB gene in nine sheep breeds or strains and its effects on litter size, lamb growth and development
Nine sheep breeds or strains, including 615 individuals were screened with forced PCR RFLP method for the FecB gene to study the polymorphism and its effects on litter sizes, body weights and body sizes. Results show that the polymorphism frequencies of FecB gene are significantly imbalanced in thes...
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| Veröffentlicht in: | Animal reproduction science 2007-05, Vol.99 (1), p.44-52 |
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| creator | Guan, Feng Liu, Shou-Ren Shi, Guo-Qing Yang, Li-Guo |
| description | Nine sheep breeds or strains, including 615 individuals were screened with forced PCR RFLP method for the
FecB gene to study the polymorphism and its effects on litter sizes, body weights and body sizes. Results show that the polymorphism frequencies of
FecB gene are significantly imbalanced in these breeds or strains. The Hu sheep were all homozygous carriers (BB). In the Chinese Merino prolific meat strain, the genotype frequencies of BB, B+ and ++ are 51%, 30% and 19%, respectively, whereas all the other flocks had only the wild-type (++) genotype. Results within Chinese Merino prolific meat strain showed that mean litter sizes of ewes with genotype BB and B+ are 2.8 (±0.74) and 2.3 (±0.63) (
P
>
0.05), whereas ++ ewes had a litter size of only 1.2 (±0.68) (
P
<
0.01). At 90 days after birth, the body weights of BB/B+ lambs were higher than that of ++ lambs (18.6
±
3.70
kg, 18.0
±
3.71
kg versus 15.6
±
2.22
kg,
P
<
0.05). In addition, the heart girth and chest width of BB/B+ lambs were significantly longer than ++ lambs (
P
<
0.05). No significant differences were observed in either body weight or body size at day 120. Litter size at first lambing from Hu at Natural Source Conservative Region was found to be significantly higher than that from the other two regions sampled (
P
<
0.05). In addition to the additive effect on litter size, these findings show for the first time that the
FecB gene had a positive effect on early postnatal body growth. |
| doi_str_mv | 10.1016/j.anireprosci.2006.04.048 |
| format | Article |
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FecB gene to study the polymorphism and its effects on litter sizes, body weights and body sizes. Results show that the polymorphism frequencies of
FecB gene are significantly imbalanced in these breeds or strains. The Hu sheep were all homozygous carriers (BB). In the Chinese Merino prolific meat strain, the genotype frequencies of BB, B+ and ++ are 51%, 30% and 19%, respectively, whereas all the other flocks had only the wild-type (++) genotype. Results within Chinese Merino prolific meat strain showed that mean litter sizes of ewes with genotype BB and B+ are 2.8 (±0.74) and 2.3 (±0.63) (
P
>
0.05), whereas ++ ewes had a litter size of only 1.2 (±0.68) (
P
<
0.01). At 90 days after birth, the body weights of BB/B+ lambs were higher than that of ++ lambs (18.6
±
3.70
kg, 18.0
±
3.71
kg versus 15.6
±
2.22
kg,
P
<
0.05). In addition, the heart girth and chest width of BB/B+ lambs were significantly longer than ++ lambs (
P
<
0.05). No significant differences were observed in either body weight or body size at day 120. Litter size at first lambing from Hu at Natural Source Conservative Region was found to be significantly higher than that from the other two regions sampled (
P
<
0.05). In addition to the additive effect on litter size, these findings show for the first time that the
FecB gene had a positive effect on early postnatal body growth.</description><identifier>ISSN: 0378-4320</identifier><identifier>EISSN: 1873-2232</identifier><identifier>DOI: 10.1016/j.anireprosci.2006.04.048</identifier><identifier>PMID: 16859845</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>additive gene effects ; animal genetics ; animal growth ; Animals ; Body size ; Body Size - genetics ; Body weight ; Body Weight - genetics ; breed differences ; China ; correlation ; DNA Primers - chemistry ; FecB gene ; Fertility - genetics ; gene frequency ; genes ; genetic polymorphism ; genotype ; Hu (sheep breed) ; lambs ; Litter size ; Litter Size - genetics ; Merino ; polymerase chain reaction ; Polymerase Chain Reaction - veterinary ; Polymorphism, Genetic - genetics ; Polymorphism, Restriction Fragment Length ; postnatal development ; postpartum period ; pregnancy outcome ; restriction fragment length polymorphism ; Sheep ; Sheep - genetics ; Sheep - growth & development ; sheep breeds ; Species Specificity ; strain differences ; strains ; Time Factors</subject><ispartof>Animal reproduction science, 2007-05, Vol.99 (1), p.44-52</ispartof><rights>2006</rights><rights>(c)2006 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c430t-c1fe5b2f362b158c6c9957aeea1e2f1df2d6431f46d28f546d7d9ecab888cd6c3</citedby><cites>FETCH-LOGICAL-c430t-c1fe5b2f362b158c6c9957aeea1e2f1df2d6431f46d28f546d7d9ecab888cd6c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.anireprosci.2006.04.048$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16859845$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Guan, Feng</creatorcontrib><creatorcontrib>Liu, Shou-Ren</creatorcontrib><creatorcontrib>Shi, Guo-Qing</creatorcontrib><creatorcontrib>Yang, Li-Guo</creatorcontrib><title>Polymorphism of FecB gene in nine sheep breeds or strains and its effects on litter size, lamb growth and development</title><title>Animal reproduction science</title><addtitle>Anim Reprod Sci</addtitle><description>Nine sheep breeds or strains, including 615 individuals were screened with forced PCR RFLP method for the
FecB gene to study the polymorphism and its effects on litter sizes, body weights and body sizes. Results show that the polymorphism frequencies of
FecB gene are significantly imbalanced in these breeds or strains. The Hu sheep were all homozygous carriers (BB). In the Chinese Merino prolific meat strain, the genotype frequencies of BB, B+ and ++ are 51%, 30% and 19%, respectively, whereas all the other flocks had only the wild-type (++) genotype. Results within Chinese Merino prolific meat strain showed that mean litter sizes of ewes with genotype BB and B+ are 2.8 (±0.74) and 2.3 (±0.63) (
P
>
0.05), whereas ++ ewes had a litter size of only 1.2 (±0.68) (
P
<
0.01). At 90 days after birth, the body weights of BB/B+ lambs were higher than that of ++ lambs (18.6
±
3.70
kg, 18.0
±
3.71
kg versus 15.6
±
2.22
kg,
P
<
0.05). In addition, the heart girth and chest width of BB/B+ lambs were significantly longer than ++ lambs (
P
<
0.05). No significant differences were observed in either body weight or body size at day 120. Litter size at first lambing from Hu at Natural Source Conservative Region was found to be significantly higher than that from the other two regions sampled (
P
<
0.05). In addition to the additive effect on litter size, these findings show for the first time that the
FecB gene had a positive effect on early postnatal body growth.</description><subject>additive gene effects</subject><subject>animal genetics</subject><subject>animal growth</subject><subject>Animals</subject><subject>Body size</subject><subject>Body Size - genetics</subject><subject>Body weight</subject><subject>Body Weight - genetics</subject><subject>breed differences</subject><subject>China</subject><subject>correlation</subject><subject>DNA Primers - chemistry</subject><subject>FecB gene</subject><subject>Fertility - genetics</subject><subject>gene frequency</subject><subject>genes</subject><subject>genetic polymorphism</subject><subject>genotype</subject><subject>Hu (sheep breed)</subject><subject>lambs</subject><subject>Litter size</subject><subject>Litter Size - genetics</subject><subject>Merino</subject><subject>polymerase chain reaction</subject><subject>Polymerase Chain Reaction - veterinary</subject><subject>Polymorphism, Genetic - genetics</subject><subject>Polymorphism, Restriction Fragment Length</subject><subject>postnatal development</subject><subject>postpartum period</subject><subject>pregnancy outcome</subject><subject>restriction fragment length polymorphism</subject><subject>Sheep</subject><subject>Sheep - genetics</subject><subject>Sheep - growth & development</subject><subject>sheep breeds</subject><subject>Species Specificity</subject><subject>strain differences</subject><subject>strains</subject><subject>Time Factors</subject><issn>0378-4320</issn><issn>1873-2232</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU-LFDEQxYMo7uzqV9B48WSP-dfp9FEHdxUWFHTPIZ1UZjJ0J23Ss7J-ejPOgN4UCt7lV_WK9xB6RcmaEirf7tcmhgxzTsWGNSNEromoox6hFVUdbxjj7DFaEd6pRnBGLtBlKXtCSCdl_xRdUKnaXol2hQ5f0vgwpTzvQplw8vga7Hu8hQg4RBxD1bIDmPGQAVzBKeOyZBNiwSY6HJaCwXuwVVPEY1gWqET4CW_waKYBb3P6sex-sw7uYUzzBHF5hp54MxZ4ftYrdHf94dvmY3P7-ebT5t1tYwUnS2Oph3Zgnks20FZZafu-7QyAocA8dZ45KTj1QjqmfFulcz1YMyilrJOWX6HXp7s1qu8HKIueQrEwjiZCOhTdEUZ61op_grTvuKAtqWB_Am0Nv2Twes5hMvlBU6KP5ei9_qscfSxHE1FH1d0XZ5PDMIH7s3luowIvT4A3SZttDkXffWWE8mNxTChZic2JgJrafYCsqwlEC65a2kW7FP7jkV_RirHO</recordid><startdate>20070501</startdate><enddate>20070501</enddate><creator>Guan, Feng</creator><creator>Liu, Shou-Ren</creator><creator>Shi, Guo-Qing</creator><creator>Yang, Li-Guo</creator><general>Elsevier B.V</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20070501</creationdate><title>Polymorphism of FecB gene in nine sheep breeds or strains and its effects on litter size, lamb growth and development</title><author>Guan, Feng ; Liu, Shou-Ren ; Shi, Guo-Qing ; Yang, Li-Guo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c430t-c1fe5b2f362b158c6c9957aeea1e2f1df2d6431f46d28f546d7d9ecab888cd6c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>additive gene effects</topic><topic>animal genetics</topic><topic>animal growth</topic><topic>Animals</topic><topic>Body size</topic><topic>Body Size - genetics</topic><topic>Body weight</topic><topic>Body Weight - genetics</topic><topic>breed differences</topic><topic>China</topic><topic>correlation</topic><topic>DNA Primers - chemistry</topic><topic>FecB gene</topic><topic>Fertility - genetics</topic><topic>gene frequency</topic><topic>genes</topic><topic>genetic polymorphism</topic><topic>genotype</topic><topic>Hu (sheep breed)</topic><topic>lambs</topic><topic>Litter size</topic><topic>Litter Size - genetics</topic><topic>Merino</topic><topic>polymerase chain reaction</topic><topic>Polymerase Chain Reaction - veterinary</topic><topic>Polymorphism, Genetic - genetics</topic><topic>Polymorphism, Restriction Fragment Length</topic><topic>postnatal development</topic><topic>postpartum period</topic><topic>pregnancy outcome</topic><topic>restriction fragment length polymorphism</topic><topic>Sheep</topic><topic>Sheep - genetics</topic><topic>Sheep - growth & development</topic><topic>sheep breeds</topic><topic>Species Specificity</topic><topic>strain differences</topic><topic>strains</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Guan, Feng</creatorcontrib><creatorcontrib>Liu, Shou-Ren</creatorcontrib><creatorcontrib>Shi, Guo-Qing</creatorcontrib><creatorcontrib>Yang, Li-Guo</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Animal reproduction science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Guan, Feng</au><au>Liu, Shou-Ren</au><au>Shi, Guo-Qing</au><au>Yang, Li-Guo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Polymorphism of FecB gene in nine sheep breeds or strains and its effects on litter size, lamb growth and development</atitle><jtitle>Animal reproduction science</jtitle><addtitle>Anim Reprod Sci</addtitle><date>2007-05-01</date><risdate>2007</risdate><volume>99</volume><issue>1</issue><spage>44</spage><epage>52</epage><pages>44-52</pages><issn>0378-4320</issn><eissn>1873-2232</eissn><abstract>Nine sheep breeds or strains, including 615 individuals were screened with forced PCR RFLP method for the
FecB gene to study the polymorphism and its effects on litter sizes, body weights and body sizes. Results show that the polymorphism frequencies of
FecB gene are significantly imbalanced in these breeds or strains. The Hu sheep were all homozygous carriers (BB). In the Chinese Merino prolific meat strain, the genotype frequencies of BB, B+ and ++ are 51%, 30% and 19%, respectively, whereas all the other flocks had only the wild-type (++) genotype. Results within Chinese Merino prolific meat strain showed that mean litter sizes of ewes with genotype BB and B+ are 2.8 (±0.74) and 2.3 (±0.63) (
P
>
0.05), whereas ++ ewes had a litter size of only 1.2 (±0.68) (
P
<
0.01). At 90 days after birth, the body weights of BB/B+ lambs were higher than that of ++ lambs (18.6
±
3.70
kg, 18.0
±
3.71
kg versus 15.6
±
2.22
kg,
P
<
0.05). In addition, the heart girth and chest width of BB/B+ lambs were significantly longer than ++ lambs (
P
<
0.05). No significant differences were observed in either body weight or body size at day 120. Litter size at first lambing from Hu at Natural Source Conservative Region was found to be significantly higher than that from the other two regions sampled (
P
<
0.05). In addition to the additive effect on litter size, these findings show for the first time that the
FecB gene had a positive effect on early postnatal body growth.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>16859845</pmid><doi>10.1016/j.anireprosci.2006.04.048</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0378-4320 |
| ispartof | Animal reproduction science, 2007-05, Vol.99 (1), p.44-52 |
| issn | 0378-4320 1873-2232 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70209254 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | additive gene effects animal genetics animal growth Animals Body size Body Size - genetics Body weight Body Weight - genetics breed differences China correlation DNA Primers - chemistry FecB gene Fertility - genetics gene frequency genes genetic polymorphism genotype Hu (sheep breed) lambs Litter size Litter Size - genetics Merino polymerase chain reaction Polymerase Chain Reaction - veterinary Polymorphism, Genetic - genetics Polymorphism, Restriction Fragment Length postnatal development postpartum period pregnancy outcome restriction fragment length polymorphism Sheep Sheep - genetics Sheep - growth & development sheep breeds Species Specificity strain differences strains Time Factors |
| title | Polymorphism of FecB gene in nine sheep breeds or strains and its effects on litter size, lamb growth and development |
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