Activating Transcription Factor 3 Is a Novel Repressor of the Nuclear Factor Erythroid-Derived 2-Related Factor 2 (Nrf2)-Regulated Stress Pathway

The transcription factor nuclear factor erythroid-derived 2-related factor 2 (Nrf2) regulates induction of an extensive cellular stress response network when complexed with the cAMP-responsive element binding protein (CBP) at antioxidant response elements (ARE) located in the promoter region of targ...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2008-01, Vol.68 (2), p.364-368
Hauptverfasser:	BROWN, Stephan L, SEKHAR, Konjeti R, RACHAKONDA, Girish, SASI, Soumya, FREEMAN, Michael L
Format:	Artikel
Sprache:	eng
Schlagworte:	Activating Transcription Factor 3 - antagonists & inhibitors Activating Transcription Factor 3 - genetics Activating Transcription Factor 3 - metabolism Activating Transcription Factor 3 - physiology Animals Antineoplastic agents Antioxidants - pharmacology Biological and medical sciences Cells, Cultured Gene Expression Regulation Medical sciences Mice NF-E2-Related Factor 2 - antagonists & inhibitors NF-E2-Related Factor 2 - metabolism NF-E2-Related Factor 2 - physiology Pharmacology. Drug treatments Protein Binding Repressor Proteins - metabolism Repressor Proteins - physiology Response Elements - drug effects RNA, Small Interfering - pharmacology Signal Transduction - genetics Stress, Physiological - genetics Transfection Tumors
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