The effect of glow discharge plasma surface modification of polymers on the osteogenic differentiation of committed human mesenchymal stem cells

Little is known of the effect of material surfaces on stem cell differentiation. The present study has addressed the hypothesis that the interaction of mesenchymal stem cells (MSCs) with material surfaces modified by glow discharge plasma is a major regulator of osteogenic differentiation. We found...

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Veröffentlicht in:	Biomaterials 2006-04, Vol.27 (10), p.2258-2264
Hauptverfasser:	Mwale, Fackson, Wang, Hong Tian, Nelea, Valentin, Luo, Li, Antoniou, John, Wertheimer, Michael R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Ammonia - chemistry Biomarkers - metabolism Cell differentiation Cell Differentiation - physiology Cells, Cultured Core Binding Factor Alpha 1 Subunit - genetics Core Binding Factor Alpha 1 Subunit - metabolism Gene Expression Glow discharge plasma Humans Mesenchymal stem cells Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - physiology Middle Aged Osteocalcin - genetics Osteocalcin - metabolism Osteogenesis Osteogenesis - physiology Polymers - chemistry Polymers - metabolism Reverse Transcriptase Polymerase Chain Reaction Surface Properties Tissue engineering
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