Omega-3 polyunsaturated fatty acid supplementation reduces hypertension in TGR(mRen-2)27 rats

Abstract To establish the effect of dietary ω -3 PUFA on angiotensin II (ANG II)-mediated hypertension, male TGR (mRen-2)27 (Ren-2) rats (animals with high ANG II activity) were maintained on a diet either deficient or sufficient in ω -3 PUFA from conception. Half the animals on each diet were treat...

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Veröffentlicht in:	Prostaglandins, leukotrienes and essential fatty acids leukotrienes and essential fatty acids, 2008-01, Vol.78 (1), p.67-72
Hauptverfasser:	Jayasooriya, A.P, Begg, D.P, Chen, N, Mathai, M.L, Sinclair, A.J, Wilkinson-Berka, J, Wark, J.D, Weisinger, H.S, Weisinger, R.S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - drug effects Advanced Basic Science Angiotensin II - blood Angiotensin-Converting Enzyme Inhibitors - therapeutic use Animals Antihypertensive Agents - pharmacology Antihypertensive Agents - therapeutic use Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood Pressure - drug effects Body Weight - drug effects Cardiology. Vascular system Eating - drug effects Endocrinology & Metabolism Experimental diseases Fatty Acids, Omega-3 - administration & dosage Fundamental and applied biological sciences. Psychology Hypertension - blood Hypertension - diet therapy Hypertension - drug therapy Hypertension - therapy Male Medical sciences Perindopril - therapeutic use Rats Renin - blood Vertebrates: endocrinology
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