Distribution coefficient of rifabutin in liposome/water system as measured by different methods

Distribution coefficient ( D) of rifabutin in liposome/water system was measured by phase separation and fluorescence probe quenching techniques. D values were identical suggesting that rifabutin is fully immersed into lipid bilayer. Structural studies of phospholipid bilayer employing 31P NMR spect...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2008-02, Vol.68 (2), p.400-405
Hauptverfasser:	Vostrikov, Vitaly V., Selishcheva, Alla A., Sorokoumova, Galina M., Shakina, Yulia N., Shvets, Vitaly I., Savel’ev, Oleg Yu, Polshakov, Vladimir I.
Format:	Artikel
Sprache:	eng
Schlagworte:	31P NMR Antitubercular Agents - pharmacokinetics Distribution coefficient Fluorescence Lipid Bilayers Liposomes Rifabutin Rifabutin - pharmacokinetics Water - chemistry
Online-Zugang:	Volltext
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