Molecular cloning and characterization of rat LC3A and LC3B—Two novel markers of autophagosome

Rat microtubule-associated protein light chain 3 (LC3) is a homologue of yeast Atg8, an essential component of autophagy. Following synthesis, the C-terminus of rat LC3 is cleaved by a cysteine protease-Atg4, to produce LC3-I, which is located in cytosolic fraction. LC3-I can be converted to LC3-II...

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Veröffentlicht in:	Biochemical and biophysical research communications 2006-01, Vol.339 (1), p.437-442
Hauptverfasser:	Wu, Jiaxue, Dang, Yongjun, Su, Wei, Liu, Chao, Ma, Haijie, Shan, Yuxi, Pei, Yuan, Wan, Bo, Guo, Jinhu, Yu, Long
Format:	Artikel
Sprache:	eng
Schlagworte:	Alternative Splicing Amino Acid Sequence Animals Autophagy Autophagy-Related Protein 8 Family Cell Line Cloning, Molecular Humans Intracellular Membranes - metabolism LC3A LC3B Microtubule-Associated Proteins - genetics Microtubule-Associated Proteins - metabolism Molecular Sequence Data Mutation Organ Specificity Phagosomes - metabolism Post-translational modification Protein Processing, Post-Translational Rat LC3 Rats Saccharomyces cerevisiae Proteins - genetics Sequence Homology, Amino Acid Subcellular localization
Online-Zugang:	Volltext
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