Endogenous channels in HEK cells and potential roles in HCN ionic current measurements

A transformed line of human embryonic kidney epithelial cells (HEK 293) is commonly used as an expression system for exogenous ion channel genes. Previously, it has been shown that these cells contain mRNAs for a variety of ion channels. Expression of some of these genes has been confirmed at the pr...

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Veröffentlicht in:	Progress in biophysics and molecular biology 2006, Vol.90 (1), p.26-37
Hauptverfasser:	Varghese, Anthony, TenBroek, Erica M., Coles, James, Sigg, Daniel C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Cyclic Nucleotide-Gated Cation Channels HCN channels HEK cells Humans Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels Ion Channel Gating Ion Channels - physiology Muscle Proteins - physiology Patch-Clamp Techniques Potassium Channels Potassium Channels, Voltage-Gated - physiology Potassium currents
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