The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons

Cortical interneurons in rodents are generated in the ventral telencephalon and migrate tangentially into the cortex. This process requires the coordinated action of many intrinsic and extrinsic factors. Here we show that Robo1 and Robo2 receptor proteins are dynamically expressed throughout the per...

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Veröffentlicht in:	Developmental biology 2008-01, Vol.313 (2), p.648-658
Hauptverfasser:	Andrews, William, Barber, Melissa, Hernadez-Miranda, Luis R., Xian, Jian, Rakic, Sonja, Sundaresan, Vasi, Rabbitts, Terence H., Pannell, Richard, Rabbitts, Pamela, Thompson, Hannah, Erskine, Lynda, Murakami, Fujio, Parnavelas, John G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers Calbindins Cell Culture Techniques Cell Differentiation Cell Movement Cell Proliferation Cells, Cultured Cerebral Cortex - cytology DNA, Complementary Electroporation Embryo, Mammalian Embryonic Stem Cells - chemistry Embryonic Stem Cells - metabolism Genetic Markers Genetic Vectors Genomic Library Immunohistochemistry Integrases - metabolism Intercellular Signaling Peptides and Proteins - genetics Intercellular Signaling Peptides and Proteins - metabolism Intercellular Signaling Peptides and Proteins - physiology Interneuron Interneurons - cytology Interneurons - physiology Kinetics Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Morphology Mutation Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Nerve Tissue Proteins - physiology Receptors, Immunologic - genetics Receptors, Immunologic - metabolism Receptors, Immunologic - physiology Robo Roundabout Proteins S100 Calcium Binding Protein G - metabolism Selection, Genetic Signal Transduction Slit Telencephalon - cytology Transfection
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